Education

DEGREES

B.S., Chemistry and Biological Sciences, Stanford University, Stanford, Ca. 1980

M.Phil., Pharmacology, City University of New York, N.Y., N.Y. 1984

Ph.D., Pharmacology, City University of New York, N.Y., N.Y. 1986

M.D., M.D.-Ph.D. program, Mount Sinai School of Medicine, N.Y. 1987

HONORS

Graduated with Distinction from Stanford University, 1980.

Doctoral Dissertation Award for best thesis, Mount Sinai School of Medicine, 1986.

NIH Student Exchange Program-Elective in Endocrinology, 1986.

Hadassah Hospital Student Exchange Program, Jerusalem, Israel, 1987.

TRAINEESHIPS

RESIDENCY at University of Michigan Hospitals, 1987-1989 Internal Medicine Ann Arbor, MI.

FELLOWSHIP at National Institutes of Health, National Institute of Child Health and Human Development, Bethesda, MD. 1989-1992 Endocrinology

SENIOR STAFF FELLOW at National Institutes of Health, National Institute of Child Health and Human Development, Bethesda, MD. 1992-1995 Endocrinology

CBS Early Show with Dr. Friedman

Ph.D. THESIS

Studies on the Effects of Inhibitors of TR4-degrading Enzymes 1982-1985.

Preceptor: Sherwin Wilk, Ph.D.

Department of Pharmacology, Mount Sinai School of Medicine

PROFESSIONAL EXPERIENCE

LICENSURE & BOARD CERTIFICATION

California State License #G81765 1995-
DEA # BF4533495

Internal Medicine 1990 (recertified 2001-2011)

Endocrinology, Diabetes and Metabolism 1993 (recertified 2003-2013, 2013-2023, 2023-2033)

MEMBERSHIPS

Endocrine Society, 1990-
Los Angeles Cross Town Endocrine Club, 1995-
American Diabetes Association, 1996-
AACF, 2002-
Los Angeles Reproductive Endicrinology Club
(founder and president), 2002-

EDITORIAL ACTIVITIES

Journal of Clinical Endocrinology and Metabolism, 10/04-2008.

Ad-hoc reviewer for:

Endocrinology, 01/95-

Journal of Clinical Endocrinology and Metabolism, 01/95-

Peptides, 01/95-

Pharmacology Biochemistry and Behavior, 06/97-

Journal of Clinical Investigation, 07/00-

Journal of Molecular Endocrinology, 12/01-

Diabetes Care, 01/03-

Journal of the National Medical Association, 01/05-

Clinical Endocrinology, 06/05-

PNAS, 01/07-

Molecular Endocrinology, 09/07-

American Journal Of Physiology- Endocrinology, 08/09-

Hospital Physician, 03/08

European Journal of Pain, 01/10

Annals of Internal Medicine, 06/10

Neuropeptides, 03/11-

PLOS, 03/12-

COMMUNITY SERVICE

Beverly Hills/Los Angeles Eruv Committee, 6/95-1/00.

Aish Hatorah Synagogue Friday Night Outreach Program, 10/96-1999.

Assemblyman Dymally’s Task Force on Improving, 9/03-06.

King/Drew Medical Center

California Legislative Black Caucus Foundation Advisory Board, 2008-2012.

Member Advisory Board Member: Special Needs Network, 2010-

GRANT REVIEWER

Ad-hoc reviewer for Canadian Diabetes Association, 2000.
Ad-hoc reviewer for IFCN-2 Study section, 2000.
Reviewer for Special Study Section on Gene Therapy and Diabetes, 2001.
Ad-hoc reviewer for the Hospital for Sick Children Foundation, 2001.
Mail reviewer for CEBRA (Cutting Edge Basic Research Awards- NIDA, 2003.

AWARDS AND RECOGNITION

“Endocrinology Under 35” Meeting, Best Poster Award,Rapallo Italy, 1992.
Outstanding Achievements in Promoting Black Employees Award, 1993.
Charles E. Culpeper Foundation Research Fellow, 1996-1998.
Mentor Drew Magnet High School Program, 2000-
Mentor of Melo Yap, 3rd place winner of the Biochemistry category, LA County Science Fair for high school students, 2001.

COMMITTEE SERVICE

Cedars-Sinai Medical Center Education Committee, 9/96-2000.

Cedars-Sinai Medical Center Medical Informatics QAT, 9/97-2000.

The Charles Drew University Animal Care Committee, 2000-2002.

The Charles Drew University MBRS Advisory Committee, 2002-2009.

Charles R. Drew University DIDARP Advisory Committee, 2004-

CSUSB DIDARP Advisory Committee, 2012-

UTEP DIDARP Advisory Committee, 2011-

The Charles Drew University RIMI Advisory Committee, 2004-2009.

The Charles Drew University RCMI Advisory Committee, 2004-2008.

The Charles Drew University Research Executive Committee, 2004-

The Charles Drew University Clinical Research Advisory Committee (Vice-chair), 2004-2009.

The Charles Drew University Research Building Committee, 2004-2006.

The Charles Drew University Space Committee, 2004-2008.

The Charles Drew University Western Association of Schools

and Colleges (WASC) re-accreditation task force, 2006-2009.

The Charles Drew University Strategic Planning for Research

task force, 2006-2012.

The Charles Drew University Faculty Senate-Chairman of Research Committee, 2007-2010.

Charles R. Drew University College of Medicine, Faculty, 2012-

Executive Board (chairman representative)

Charles Drew University/MLK MACC Internal Medicine, 2013-

Grand Rounds Committee Chair

UCLA CTSI KL2 committee, 2013-

Charles R. Drew University Patent Committee, 2014-

Charles R. Drew University LSI Committee, 2014-

Charles R. Drew University AXIS Committee, 2014-

Charles R. Drew University Longitudinal Education Committee, 2015-

ADVISORY BOARD

ProStrakan Pharmaceuticals 2007

Corcept Pharmaceuticals 2011-

Tirosint Advisory Board 2014

Somavert Advisory Board 2015

Somavert Advisory Board 2016

POSITION HELD

Charles R. Drew University of Medicine & Science, 2013-

Professor of Medicine-Career Academic Series, Step 2

Endocrinology Division

Los Angeles, CA

David Geffen School of Medicine at UCLA, 2012-

Professor of Medicine-In-Residence Series, Step 2

Los Angeles, CA

David Geffen School of Medicine at UCLA, 2008-2012.

Professor of Medicine-In-Residence Series, Step 1

Los Angeles, CA

The Charles Drew University of Medicine & Science, 2008-

Professor of Medicine-Career Academic Series, Step 1

Endocrinology Division

Los Angeles, CA

David Geffen School of Medicine at UCLA, 2006-2008.

Associate Professor of Medicine-In-Residence Series, Step III (accelerated promotion)

Los Angeles, CA

The Charles Drew University of Medicine & Science, 2005-2008.

Associate Professor of Medicine-Career Academic Series, Step 3 (accelerated promotion)

Endocrinology Division

Los Angeles, CA

David Geffen School of Medicine at UCLA, 2002-2006.

Associate Professor of Medicine-In-Residence, Step I

Endocrinology Division

The Charles Drew University of Medicine & Science

Los Angeles, CA

David Geffen School of Medicine at UCLA, 2000-2002.

Assistant Professor of Medicine-In-Residence, Step IV

Endocrinology Division

The Charles Drew University of Medicine & Science

Los Angeles, CA

David Geffen School of Medicine at UCLA, 1997-2000.

Assistant Professor of Medicine-Step IV

Endocrinology Division

Cedars-Sinai Medical Center

Los Angeles, CA

David Geffen School of Medicine at UCLA, 1995-1997.

Assistant Professor-in-Residence of Medicine, Step III

Endocrinology Division

Cedars-Sinai Medical Center

Los Angeles, CA

The Charles Drew University of Medicine & Science, 2008-

Chairman, Department of Internal Medicine (54 faculty members)

David Geffen School of Medicine at UCLA, 2008-

Vice Chair, Department of Medicine

The Charles Drew University of Medicine & Science, 2007-2008.

Interim Chairman, Department of Internal Medicine

The Charles Drew University of Medicine & Science, 2005-

Chief, Division of Endocrinology, Molecular Medicine and Metabolism (45 member division, 17 faculty)

Martin Luther King, Jr. Multi-Service Ambulatory Care Center (MACC) 2005-

Lead Physician Endocrinology.

The Charles Drew University of Medicine & Science, 2005-2011.

Director, NICHD Drew/UCLA Cooperative Reproductive Science Research Center

The Charles Drew University of Medicine & Science, 2002-

Director, Minority Biomedical Research Support Program

The Charles Drew University of Medicine & Science, 2000-2004.

Director, Body Composition Core of the Drew Center of Excellence for Metabolic Research

The Charles Drew University of Medicine & Science, 2000-2005.

Director, Endocrinology Fellowship Program

Friends Research Institute-Senior Researcher, 2011-

Founder and Director-Obesity Group Visit Program at MLK-MACC 2013-

Chairman, DHS Endocrinology/Diabetes Work Group, 2013-

Cedars-Sinai Medical Center, 1998-2000.

Director, Multi-Disciplinary Chronic Fatigue Clinic

Director-Staff Wellness Program at MLK-MACC, 2014.

ENDOWMENTS

The Charles Drew University of Medicine & Science, 2007-

Endowed Professorship for Cardio-Metabolic Medicine

PATENTS

US provisional patent Serial No. 62/370.889, filed on August 4, 2016 (Inventors Friedman and Shao) “An efficient E-cigarette aerosol generation and exposure system for rodents, with properties of aerosol similar to those of aerosol inhaled by E-cigarette smokers”

US and international (PCT) patent PCT/US17/54133, filed on August 2, 2017 (Inventors Friedman and Shao) “Aerosol Generation and Exposure System”

HONORS AND SPECIAL AWARDS

Graduated with Distinction from Stanford University, 1980.

Doctoral Dissertation Award for best thesis Mount Sinai School of Medicine, 1986.

NIH Student Exchange Program-Elective in Endocrinology, 1986.

Hadassah Hospital Student Exchange Program Jerusalem, Israel, 1987.

“Endocrinology Under 35” Meeting in Rapallo Italy Best Poster Award, 1992.

Outstanding Achievements in Promoting Black Employees Award, 1993.

Charles E. Culpeper Foundation Research Fellow, 1996-1998.

Mentor Drew Magnet High School Program, 2000-

Mentor of Melo Yap, 3rd place winner of the Biochemistry category, LA County Science Fair for high school students, 2001.

Advisory Council for Western Society for Clinical Investigation, 2004-2007.

Certificate of Appreciation, NIH, NIDDK Short-Term Educational

Program for Underrepesented Persons, 2007.

Southern California Super Doctors 2008 by LA Magazine, 2008.

Franklin Covey Seven Habits for Research Managers Training, 01/2009.

Franklin Covey Four Disciplines of Execution Training, 03/2010.

Legislative Black Caucus Foundation Advisory Board Member, 2008-2010.

Legislative Black Caucus Foundation Co-Chair Health Committee, 2008-2010.

Secretary/Treasurer Western Society for Clinical Investigation, 2009-2012.

Medical Advisory Board of EmpowHer, women’s health educational website, 2009-

Mentor of Jesse Tweed, MD, winner of outstanding medical, 2012.

student senior thesis, Charles R. Drew University School of Medicine

Lead Physician: LA County DHS Endocrinology-primary care work group, 2013-

Professor of the Year: Charles R. Drew University School of Medicine, 2013.

Training to be a Champion Provider to Prevent Obesity-UCSF, 7/11/14-7/12/14.

Los Angeles County Department of Health Services 28^th annual productivity and quality award: Special Merit Plaque Winner POWER Group Visit Combats Obesity, 10/22/14.

Outstanding Service Award: College of Medicine, Charles R. Drew University School of Medicine, 2015.

Masters Theses Successfully defended.

Student	Institution	Date of Defense	Title
Rasheed Ivey	Cal State University-Dominguez Hills	May 8, 2012	Nicotine in Conjunction With a High Fat Diet Exacerbates Hepatic Steatosis in a Mouse Model
Desean L. Lee	Cal State University-Dominguez Hills	May 8, 2013	PC2 Null Mice Show Up-Regulation Of The Mu Opioid Receptor In Key Brain Regions Related To Nociceptive Information And Addictive Behaviors
Tiffany Allen	Cal State University-Dominguez Hills	May 8, 2014	Differential Regulation of PC 1/3 and MOR in the Nucleus Accumbens, Arcuate Nucleus and Lateral Septal Nucleus
Meera Desai	Cal State University-Dominguez Hills	April 17, 2015	Nicotine and High-Fat Diet Induces Hepatocyte Cell Death Through Intrinsic and Extrinsic Apoptotic Pathway Signaling
Perla Saldivar	Master of Science in Biomedical Sciences, College of Science and Health: Charles R. Drew University	August 10, 2017	Making An Underserved Population In South Los Angeles Healthier: Implementing A Texting Program In The P.O.W.E.R. (Preventing Obesity With Eating Right) Medical Group Visits
Zena Simmons	Master of Science in Biomedical Sciences, College of Science and Health: Charles R. Drew University	August 10, 2017	Cardiovascular Effects Of E-Cigarettes On Apolipoprotein E Null Mice When Fed A Western Diet

Research Grants

RESEARCH GRANTS RECEIVED

California Tobacco-Related Disease Research Program (TRDRP) Grant 251P003 –PI Friedman

Metabolic and Carcinogen Effect of Electronic Cigarettes

7/1/16-6/30/18

Direct Costs $298,027/Total Costs $321,254

UCLA Clinical and Translational Science Institute, PI: Friedman

An Animal Model for Delivering Electronic Cigarettes

3/1/15- 2/29/16

Direct Costs-$16,666/Total Costs $16,666

NIH R21 DA022342-01 PI-Friedman

The mechanisms of the nicotine-induction of insulin resistance

9/30/07-8/31/11

Direct Costs $250,000, Total costs $353,021

NIH K01 DK073272-01, Mentor (PI: Yanjun Liu, M.D., Ph.D.)

The role of 11beta-HSD1 in type II diabetes and obesity

7/15/06-7/31/09

Direct Costs Total $367,050, Total Costs $396,414

NIH R01DA14659-01A1, PI-Friedman

Genes and Proteins Leading to Addiction

8/1/02-7/30/10

Direct Costs Total $750,000, Total Costs $1,068,750

NIH R21DA15466-01-A1 PI-Friedman

HPA axis activation and nicotine use

4/1/03-3/31/08

Direct Costs $300,000/Total Costs $427,500

NIH R21DA016867-01-A1 PI-Friedman

Chronic Nicotine’s Activation of the HPA Axis

7/1/03-6/30/07

Direct Costs $300,000/Total Costs $427,500

NIH-P20 RR11145-01 (Center of Excellence Grant), Co-investigator (PI: Francis/Norris)

Regulation of Prohormone Convertases

5/1/00-4/30/04

Direct Costs $300,000/Total Costs $435,000

Thyroid Research Advisory Council (TRAC) Research Grant, PI-Friedman

Regulation of PC1 and PC2 by Thyroid Hormone

7/1/00-9/30/02

Direct Costs $86,956/Total Costs $100,000

NIDA K21 DA00276-01, PI-Friedman

Structural Determinants in Regulation of POMC Processing

7/1/95- 6/30/01

Direct Costs-$667,628/Total Costs $721,038

Charles E. Culpeper Foundation Research Award, PI-Friedman

Structural Determinants in Regulation of Pro-opiomelanocortin Processing:Implications for Developing Novel Treatments for Drug Addiction

7/1/96- 6/30/98

Direct Costs-$200,000/Total Costs $200,000

ADA Research Grant, PI-Friedman

Disordered IGF-I Biosynthesis: Implications in the Pathogenesis of Diabetic Complications

1/1/96- 12/31/97

Direct Costs-$100,000/Total Costs $100,000

RESEARCH GRANTS SUBMITTED

NIH RO1,1 RO1 DA015769-01-A2, PI ( to be resubmitted 11/03) Regulation of PC1/PC2 by Opiates 11/1/02-10/31/05
Direct costs $525,000/Total Costs 748,125

NIH RO1,PI , Renin-Aldosterone axis in CFS (recieved a score of 260, will be resubmitted) 2/1/03-1/31/06. Direct Costs $525,000/Total Costs $748,125

Lectures and Presentations (Selected)

University of Michigan Medical Center-Endocrine Research Conference-March 10, 1994 In Vitro Processing of Pro-opiomelanocortin and Anthrax Toxin Protective Antigen by Recombinant PC1
NIH Interinstitute Endocrine Grand Rounds-April 8, 1994 In Vitro Processing of Pro-opiomelanocortin and Anthrax Toxin Protective Antigen by Recombinant PC1: Implications for Endocrine Tumor Targeting
Eli Lilly Endocrine Noon Conference-April 20, 1994 In Vitro Processing of Pro-opiomelanocortin and Anthrax Toxin Protective Antigen by Recombinant PC1
University of Colorado Medical Center- Clinical Pharmacology Seminar-July 21, 1994 In Vitro Processing of Pro-opiomelanocortin and Anthrax Toxin Protective Antigen by Recombinant PC1: Implications for Endocrine Tumor Targeting
National Heart Lung and Blood Institute Seminar-August 17, Processing of Pro-opiomelanocortin by PC1 and PC2: Implications for Processing Vasoactive Peptide Precursors
Cedars-Sinai Medical Center Special Research Seminar-December 1, 1994 Processing of Pro-opiomelanocortin by PC1 and PC2: Insights from In Vitro and Antisense Experiments
Cedars-Sinai Medical Center Endocrinology Research Seminar-May 19, 1995 The Endocrinology of Sleep
Institute de Biotechnologia/UNAM Seminar-Cuernavaca, Mexico- February 6, 1996 Biosynthesis and Processing of TRH
Cedars-Sinai Medical Center Endocrinology Research Seminar-February 9, 1996 Biosynthesis and Processing of TRH
Harbor-UCLA Medical Center Clinical Endocrinology Conference-March 13, 1996 Cushing Syndrome Versus Pseudo-Cushing State-What to do?
Cedars-Sinai Medical Center Endocrine Grand Rounds-April 16, 1996 Cushing Syndrome Versus Pseudo-Cushing State-What to do?
Hammersmith Hospital-Endocrinology Research Seminar-London, England-August 5, 1996 Prohormone Processing
University of Reading-Biochemistry and Physiology of Disease Research Group-Reading, England-August 8, 1996 POMC and ProTRH Processing
University of Bristol Medical Center-Department of Medicine Seminar-Bristol, England-August 12, 1996 The Endocrinology of Sleep
Royal Free Hospital-Endocrinology Research Seminar-London, England-August 13, 1996 Pro-Hormone Convertases
Cedars-Sinai Medical Center Endocrinology Research Seminar-September 27, 1996 Pro-hormone Processing: Advances in Basic Science and Clinical Studies
University of Southern Californai Medical Center Endocrinology, Diabetes and Hypertension Grand Rounds-October 1, 1996 Pro-hormone Processing:Advances in Basic Science and Clinical Studies
City of Hope National Medical Center Diabetes, Endocrinology and Metabolism Clinical Conference-October 2, 1996 Cushings Vs. PseudoCushings-How to Differentiate?
Wadsworth VA Medical Center Endocrine Research Seminar-October 24, 1996 Prohormone Processing:Advances in Basic Science and Clinical Studies
Cedars-Sinai Medical Center Endocrinology Journal Club-December 13, 1996 Two-Hybrid System
UCLA Interdisciplinary Pituitary Conference-January 16, 1997 Discussant on Recurrent or Persistent Cushing’s Syndrome in a 21 year old Woman
Mount Sinai School of Medicine Endocrinology Grand Rounds-February 18, 1997 Prohormone Processing:Advances in Health and Disease
The New York Hospital-Cornell Medical Center Division of Endocrinology, Diabetes and Metabolism Weekly Conference-February 19, 1997 Prohormone Processing:Advances in Basic Science and Clinical Studies
Cedars-Sinai Medical Center Endocrine Grand Rounds-March 4, 1997 Processing Enzymes in Health and Disease
Cedars-Sinai Medical Center Medical Genetics Seminar-March 13, 1997 Prohormone Processing:Advances in Basic Science and Clinical Studies
Cedars-Sinai Medical Center Endocrine Grand Rounds-March 25, 1997 The Endocrinology of Sleep
Cedars-Sinai Medical Center Endocrinology Research Seminar-October 31, 1997 Genes Involved in Spermatogenesis
UCLA Interdisciplinary Pituitary Conference-November 20, 1997 Growth Hormone Deficiency
Cedars-Sinai Medical Center Endocrine Grand Rounds-January 13, 1998 The Endocrinology of Fatigue
UCLA Interdisciplinary Pituitary Conference-May 28, 1998 Problems in the Diagnosis of Cushing’s Syndrome
The Charles Drew Endocrine Clinical Conference-June 10, 1998 Endocrinology of Fatigue
Endocrine Society “Meet the Professor”-June 24, 1998 Cushing’s Syndrome
Cedars-Sinai Medical Center Endocrine Grand Rounds-September 15, 1998 Cushings vs Pseudocushings
California Pituitary Conference -October 23, 1998 Cushing’s Disease
Cedars-Sinai Medical Center Endocrinology Research Seminar-November 6, 1998 Regulation of the Prohormone Convertases: A Novel Mechanism to Maintain Hormonal Homeostasis
Cedars-Sinai Medical Center Endocrine Grand Rounds-February 23, 1999 The Endocrinology of Chronic Fatigue
Cedars-Sinai Medical Center Endocrine Grand Rounds-May 11, 1999 Prohormone Processing
UCLA Interdisciplinary Pituitary Conference-September 30, 1999 Repeat Surgery, Radiation or Adrenalectomy in Recurrent Cushing’s Syndrome
Cedars-Sinai Medical Center Endocrine Grand Rounds-October 5, 1999 Update on Cushing’s Syndrome
California State University-LA Biology and Microbiology Seminar-November 2, 1999 Regulation of the Prohormone Convertases: A Novel Mechanism to Maintain Hormonal Homeostasis
The Charles Drew Endocrine Clinical Conference-January 6, 2000 Regulation of the prohormone convertases: A novel mechanism to maintain hormonal homeostasis in Diabetes
University of Southern California Medical Center Division of Endocrinology and Diabetes Grand Rounds-February 1, 2000 Regulation of the prohormone convertases: A novel mechanism to maintain hormonal homeostasis in Diabetes
Harbor-UCLA Medical Center Clinical Endocrinology Conference-February 23, 2000 Regulation of the prohormone convertases: A novel mechanism to maintain hormonal homeostasis in Diabetes
Cedars-Sinai Medical Center Endocrinology Research Seminar-February 25, 2000 Regulation of the prohormone convertases: A novel mechanism to maintain hormonal homeostasis in Diabetes
Wadsworth VA Medical Center Endocrine Research Seminar-June 9, 2000 Endocrinology of Chronic Fatigue.
MLK/Drew Pathophysiology Lecture Series-June 19, 2000 The Adrenal Gland.
The Charles Drew Endocrine Clinical Conference-June 28, 2000 Endocrinology of Chronic Fatigue.
The Charles Drew Emergency Medicine Conference-September11, 2000 Adrenal Insufficiency.
City of Hope Endocrine Clinical Conference- September13, 2000 Endocrinology of Chronic Fatigue.
The Charles Drew Endocrine Clinical Conference-February 21, 2001 Diagnosis of Difficult Cases of Cushing’s Syndrome.
Providence Holy Cross Medical Center Clinical Conference-March 27, 2001 The Practical Evaluation and Management of Adrenal Insufficiency for the Hospitalist and the Primary Care Physician.
The Charles Drew Endocrine Basic Conference-July 23, 2001 Hormones involved in Obesity/Role of 7B2.
National Youth Leadership Forum on Medicine-July 25, 2001 Careers in Academic Medicine.
The Charles Drew Internal Medicine Grand Rounds-September12, 2001 Adrenal Insufficiency.
Cedars-Sinai Medical Center Endocrinology Research Seminar-November 27, 2001 Endocrinology of Chronic Fatigue.
The Charles Drew Endocrine Clinical Conference-February 20, 2002 How to Diagnosis Early Cushing’s.
City of Hope Endocrine Clinical Conference- June 5, 2002 Adrenal Insufficiency.
Pituitary Patient Congress (sponsored by the Pituitary Network Association) June 27, 2002 The Logical Progression: Building your own best team for rest of life care.
Pituitary Patient Congress (sponsored by the Pituitary Network Association) June 28, 2002 Cushing’s Syndrome (session chair and keynote speaker).
National Youth Leadership Forum on Medicine-July 10, 2002 Careers in Academic Medicine.
The Charles Drew Internal Medicine Grand Rounds-September 19, 2002 Endocrinology of Chronic Fatigue.
King Drew Medical Center New Technologies in Medicine Conference-October 25, 2002 New Technologies in Endocrinology.
Harbor-UCLA Medical Center Clinical Endocrinology Conference-November 5, 2002 Everything you Need to Know to Diagnose Cushing’s Syndrome.
Cedars-Sinai Medical Center Endocrinology Grand Rounds-March 4, 2003 Renin/Aldosterone Axis in Chronic Fatigue Syndrome.
West LA VA Medical Center Endocrine Research Seminar-March 14, 2003 Cushing’s Syndrome.
Women’s Sexual Health State-of-the-Art Series (Santa Monica, CA)-March 16, 2003. Assays and Measurement Issues: Can Androgen Deficiency Be Reliably Addressed in Women?
Harbor-UCLA Medical Center Internal Medicine Grand Rounds-April 1, 2003 Comprehensive Hormone Replacement in Patients with Hypopituitarism.
UCLA Pituitary Patient Care Support-April 10, 2003 Hormone Replacement in Patients with Hypopituitarism-We Simply Need to Do More.
The Charles Drew Endocrine Clinical Conference-May 21, 2003 Nuances of Hormone Replacement for Hypopituitarism-part I.
The Charles Drew Endocrine Clinical Conference-June 4, 2003 Nuances of Hormone Replacement for Hypopituitarism-part II.
New Jersey Medical School-War Related Illnesses Special Conference-June 25, 2003 Endocrine Causes of Chronic Fatigue.
The Charles Drew Endocrine Division of Research Grant Writing Series-July 21, 2003-Specific Aims and Hypothesis.
The Charles Drew Endocrine Division of Research Grant Writing Series-July 28, 2003-Background and Preliminary Data.
The Charles Drew Endocrine Division of Research Grant Writing Series-August 4, 2003-Methods.
The Charles Drew Endocrine Division of Research Grant Writing Series-August 18, 2003-Resubmissions.
West LA VA Medical Center Endocrine Research Seminar-September 4, 2003 Nuances of Hormone Replacement for Hypopituitarism-part I.
Cedars-Sinai Medical Center Endocrinology Grand Rounds-September 30, 2003 Nuances of Hormone Replacement for Hypopituitarism-part I.
Cedars-Sinai Medical Center Endocrinology Grand Rounds-October 14, 2003 Nuances of Hormone Replacement for Hypopituitarism-part II.
Providence Holy Cross Medical Center Clinical Conference-October 21, 2003 Diagnosis & Management Of Adrenal Insufficiency In Hospitalized Patients.
The Charles Drew Endocrine Research Conference-October 27, 2003 Changing Faces of Cushing’s Syndrome-A Difficult to Diagnose Disease Becomes More Difficult.
Orange County Endocrine Society Research Presentation-November 5, 2003 Nuances of Hormone Replacement for Hypopituitarism.
SCPMG Kaiser Regional Diabetes & Endocrinology Meeting, November 18, 2003 Hypercortisolism: Diagnosis, Review of Laboratory Tests Including Salivary Cortisol, and Management.
Medical College of Wisconsin Endocrinology Research Conference, February 9, 2004 The Role of Prohormone Processing Enzymes in the Pathogenesis of Diabetes and Obesity.
South Coast Medical Center Medicine Grand Rounds, March 9, 2004 What Can Growth Hormone Really Do? Proper Diagnosis and Management of Adult Growth Hormone Deficiency
University of Colorado Health Sciences Center, Barbara Davis Center Research Conference, March 19, 2004 The Role of Prohormone Processing Enzymes in the Pathogenesis of Diabetes and Obesity.
The Charles Drew Endocrine Clinical Conference-June 2, 2004 What Can Growth Hormone Really Do? Proper Diagnosis and Management of Adult Growth Hormone Deficiency
University of California, Irvine, Endocrinology Research Conference, June 2, 2004 The Role of Prohormone Processing Enzymes in the Pathogenesis of Diabetes and Obesity.
Orange County Endocrine Society Research Presentation-July 7, 2004 Changing Faces of Cushing’s Syndrome.
Gordon Research Conference on Proprotein Processing, Trafficking and Secretion-July 12, 2004 Role of Prohormone Convertase 1 in Obesity and Diabetes.
The Charles Drew Endocrine Clinical Conference-July 21, 2004 Adrenal Insufficiency.
Harbor-UCLA Medical Center Clinical Endocrinology Conference- July 28, 2004 Proper Diagnosis and Management of Adult Growth Hormone Deficiency
The Charles Drew Internal Medicine Emergency Lectures-August 30, 2004 Adrenal Insufficiency.
The Charles Drew Endocrine Research Conference-November 8, 2004 Cushing’s Syndrome: An elusive zebra or a white horse with one black strip.
The Charles Drew Internal Medicine Grand Rounds-November 16, 2004 Cushing’s Syndrome: An elusive zebra or a white horse with one black strip.
OHSU Endocrinology Conference-November 22, 2004 Physiological Testosterone Replacement in Women with Hypopituitarism: Is it Time?
UCLA Medical Student Lecture-January 12, 2005 The Adrenal Glands: Physiology, Pathophysiology and Tumors (provided slides)
King-Drew Magnet High School Special Class February 10, 2005 Drug Addiction is a Brain Disease: Understanding Drug Addiction and Approach to Research
CSUDH Biomedical Research Forum February 10, 2005 Drug Addiction is a Brain Disease: Understanding Drug Addiction and Approach to Research
The Charles Drew MSCR/MBRS Seminar March 2, 2005 Drug Addiction is a Brain Disease: Understanding Drug Addiction and Approach to Research
Western University School of Pharmacy Special Symposium March 31, 2005 How to Write a Successful Grant
The Charles Drew Allied Health Substance Abuse Counselors Class April 7, 2005 Drug Addiction is a Brain Disease: Understanding Drug Addiction and Approach to Research
West LA VA Medical Center Residents Conference April 18, 2005 The Adrenal Glands: Physiology and Pathophysiology
The Charles Drew MBRS Seminar April 20, 2005 The Ins And Outs Of Publishing
West LA VA Medical Center Residents Conference April 21, 2005 The Adrenal Glands: Physiology and Pathophysiology
NIH Reproductive Center Program Director’s Meeting May 19, 2005 Physiologic Testosterone Replacement in Women with Hypopituitarism
West LA VA Medical Center Endocrinology Grand Rounds May 20, 2005 Cushing’s Syndrome: An elusive zebra or a white horse with one black strip.
The Charles Drew Endocrine Clinical Conference-July 27, 2005 An update on the Diagnosis of Cushing’s Syndrome.
The Charles Drew Internal Medicine Emergency Lectures-August 8, 2005 Adrenal Insufficiency.
Harbor-UCLA Endocrine Clinical Conference-September 28, 2005 An update on the Diagnosis of Cushing’s Syndrome.
The Charles Drew University Research Administration 2006 Seminar Series January 20, 2006 NIH Peer Review Process
Western Society for Clinical Investigation State-of-the-Art Lecture-February 3, 2006 Mild And/Or Periodic Cushing’s Syndrome: A Paradigm For Diagnosing Mild Metabolic Diseases.
MAGIC Foundation’s Affected Adult Convention (Phoenix) February 5, 2006 Reproductive Health.
MAGIC Foundation’s Affected Adult Convention (Phoenix) February 5, 2006 How to Deal With Your Doctor and Why Are So Few Endocrinologists Treating Adults?
MAGIC Foundation’s Affected Adult Convention (Phoenix) February 5, 2006 Treatment of Multiple Endocrine Problems.
The Charles Drew Medical School 3^rd Year Medical Student Lecture February 13, 2006 Drug Addiction is a Brain Disease: Understanding Drug Addiction and Approach to Research
West LA VA Medical Center Endocrinology Grand Rounds March 3, 2006 Physiologic Testosterone Replacement in Women with Hypopituitarism: Is it Time?
NIH Reproductive Center Program Director’s Meeting May 17, 2006 Physiologic Testosterone Replacement in Women with Hypopituitarism, An Update.
NIH Reproductive Center Program Director’s Meeting May 17, 2006 Biological Effects of Androgens in Men and Women, An Overview.
Laboratory of Developmental Neurobiology-NIH Special Lecture May 18, 2006 11b-HSD: Role in Diabetes and Nicotine Addiction
The Charles Drew Internal Medicine Grand Rounds May 23, 2006 Physiologic Testosterone Replacement in Women with Hypopituitarism: Is it Time?
Cortisol Secretion Abnormalities-1; 25 years studying stress mediators symposium!-Honoring George Chrousos, M.D., June 23, 2006 Periodic Cushing’s Syndrome: Lessons from George.
The Charles Drew Endocrine Research Conference-October 9, 2006 Regulation of PC1/3, PC2 and phosphorylated CREB by short-term and long-term morphine treatment: Implications for Understanding the “Switch” to Opiate Addiction
Harbor/UCLA Basic Science Research Lecture-October 24, 2006 Regulation of PC1/3, PC2 and phosphorylated CREB by short-term and long-term morphine treatment: Implications for Understanding the “Switch” to Opiate Addiction
Drew Research Retreat-November 2, 2006 Division of Endocrinology Update
CSUDH Biomedical Research Seminar December 7, 2006 Regulation of PC1/3, PC2 and phosphorylated CREB by short-term and long-term morphine treatment: Implications for Understanding the “Switch” to Opiate Addiction.
The Cleveland Clinic Endocrinology Grand Rounds February 23, 2007 11b-HSD1: Role in Diabetes and Nicotine-Induced Insulin-Resistance .
Center for Androgen –Related Disorders (CARD) Lecture Series- Cedars-Sinai Medical Center March 6, 2007 Physiological Testosterone Replacement in Women with Hypopituitarism: Is it Time?
The Charles Drew Endocrinology Research Conference March 8, 2007 11b-HSD1: Role in Diabetes and Nicotine-Induced Insulin-Resistance
The Charles Drew The RCMI-Faculty Development Core July 13, 2007 Lessons from the Cuban Healthcare and Medical Education Systems
The Charles Drew Life Sciences Seminar for Clinicians and Researchers July 18, 2007 Supplements-Pros and Cons (with Gail Orum Alexander, Pharm.D.)
3rd Annual The Charles Drew Drug Abuse Research Symposium September 7, 2007 Nicotine-Induced Insulin-Resistance In Mice and Men
Providence Holy Cross Medical Center CME Lecture October 23, 2007 Endocrine Incidentalomas: Thyroid, Adrenal and Pituitary
Legislative Black Caucus Foundation: Diabetes/Obesity Health Summit December 5, 2007. Willowbrook Health Center
Legislative Black Caucus Foundation: Diabetes/Obesity Health Summit December 5, 2007. Vitamin D Supplementation to Prevent Diabetes in Blacks
Legislative Black Caucus Foundation: Diabetes/Obesity Health Summit December 5, 2007. Where do we go from here?
The Charles Drew University Life Sciences Seminar for Clinicians and Researchers April 9, 2008 Bioidentical Estrogen for Hot Flushes
Huntington Hospital CME Lecture May 2, 2008 Adrenal and Pituitary Incidentalomas
Harbor-UCLA Endocrine Grand Rounds May 7, 2008 Adrenal and Pituitary Incidentalomas
MLK Ambulatory Care Clinic Medicine Grand Rounds May 28, 2008 Bioidentical Estrogen for Hot Flushes
West LA-VA Endocrine Grand Rounds June 20, 2008 Bioidentical Estrogen for Hot Flushes
Harbor-UCLA Endocrine Grand Rounds Endocrine Grand Rounds October 29, 2008 Bioidentical Estrogen for Hot Flushes
MLK Ambulatory Care Clinic Medicine Grand Rounds October 31, 2008 Adrenal and Pituitary Incidentalomas
University of Texas-El Paso Psychology Division Research Presentation December 8, 2008 Nicotine-Induced Insulin-Resistance In Mice and Men
The Charles Drew Endocrine/Cardio-metabolic Research Conference-December 11, 2008 Nicotine-Induced Insulin-Resistance In Mice and Men
MAGIC Foundation’s Affected Adult Convention (Las Vegas) February 22, 2009 Diagnosing Cushing’s syndrome: Not as easy as it seems.
MAGIC Foundation’s Affected Adult Convention (Las Vegas) February 22, 2009 Determining the type of Cushing’s syndrome: Not as hard as it seems.
MAGIC Foundation’s Affected Adult Convention (Las Vegas) February 22, 2009 Cushing’s syndrome: So you had your surgery-now what?
MAGIC Foundation’s Affected Adult Convention (Las Vegas) February 22, 2009 Beyond pituitary surgery: radiosurgery vs. adrenalectomy when Cushing’s disease persists or recurs.
University of Toledo Research Conference March 2, 2009 Nicotine and Insulin Resistance: The Key Link Between Cigarette Smoking and Heart Disease/Diabetes?
The Charles Drew University Cardio-metabolic Cluster Journal Club April 2, 2009 Paired box 6 (PAX6) regulates glucose metabolism via proinsulin processing mediated by prohormone convertase 1/3 (PC1/3)
The Charles Drew University Cardio-metabolic Cluster Seminar for Clinicians and Researchers April 23, 2009 Update on Episodic Cushing’s Syndrome
Children’s Hospital of Los Angeles Pediatric Endocrinology Grand Rounds July 2, 2009 Cushing’s Syndrome: An elusive zebra or a white horse with one black strip.
UC-Davis Internal Medicine Grand Rounds September 3, 2009 Physiological Testosterone Replacement in Women with Hypopituitarism: Is it Time?
St. Louis University Endocrine Research Conference September 16, 2009 Nicotine and Insulin Resistance: The Key Link Between Cigarette Smoking and Heart Disease/Diabetes?
Department of Obstetrics and Gynecology Grand Rounds David Geffen School of Medicine at UCLA October 30, 2009 Physiological Testosterone Replacement in Women with Hypopituitarism: Is it Time?
The Charles Drew University Cardio-metabolic Cluster Meeting November 19, 2009 NIH Restructured Application Process.
Endocrine Grand Rounds Division of Endocrinology & Metabolism at UCSD/VASDHS December 2, 2009 Cushing’s Syndrome: An elusive zebra or a white horse with one black strip.
Charles Drew University MBRS PRIDE lecture series. January 20, 2010 “Grantsmanship and Grantwriting,” Pt 1-Specifis Aims and Hypothesis.
Charles Drew University MBRS PRIDE lecture series. February 3, 2010 “Grantsmanship and Grantwriting,” Pt 2. Significance/Preliminary Data/Approach/Budgets
Charles Drew University MBRS PRIDE lecture series. February 10, 2010 “Grantsmanship and Grantwriting,” Pt 3. Resubmissions/ Biosketch/Resources.
Providence Holy Cross Medical Center CME Lecture. March 5, 2010. Adrenal Insufficiency in the Outpatient and Inpatient Settings.
CDU Cross-disciplinary lecture series. March 17, 2010. Decreased Prevalence of Diabetes in Marijuana Users: Data from NHANES III (co-presented with Magda Shaheen and Tripathi Rajavashisth)
RTRN Symposium at CDU. March 23, 2010. Treatment of Hypovitaminosis D and Prediabetes in Minorities: A Pilot study.
Charles Drew University MBRS PRIDE lecture series. March 24, 2010 “Grantsmanship and Grantwriting,” Pt 4. How to Respond to an RFA.
Metabolic Interest Group: University of Colorado School of Medicine. April 1, 2010. Nicotine, Non-alcoholic fatty liver disease and Insulin Resistance: The Key Link Between Cigarette Smoking and Heart Disease/Diabetes?
1^st Annual AXIS Translational Research Day at CDU. April 9, 2010. Nicotine, Non-alcoholic fatty liver disease and Insulin Resistance: The Key Link Between Cigarette Smoking and Heart Disease/Diabetes?
The Charles Drew University Office of Sponsored Programs Special Lecture April 22, 2010 NIH Restructured Application Process.
Harbor-UCLA-Medical Center, Endocrine Clinical Conference. May 5, 2010. Adrenal Insufficiency in the Outpatient and Inpatient Settings.
MAGIC Foundation’s Affected Adult Convention (Chicago) June 13, 2010 How to Live to 100!
MAGIC Foundation’s Affected Adult Convention (Chicago) June 13, 2010 Adrenal insufficiency-How to diagnose, treat and manage.
Charles Drew University Physician’s Assistant Course June 23, 2010 Adrenal insufficiency-How to diagnose, treat and manage.
6th Annual The Charles Drew Drug Abuse Research Symposium August 13, 2010 Decreased Prevalence of Diabetes in Marijuana Users: Data from NHANES III
Charles Drew University Cross-disciplinary Lecture Series August 18, 2010 How to Live to 100! (part 1)
University of Wisconsin School of Medicine and Public Health Endocrinology Grand Rounds. August 23, 2010. Nicotine, Non-alcoholic fatty liver disease and Insulin Resistance: The Key Link Between Cigarette Smoking and Heart Disease/Diabetes?
UCLA Family Medicine Grand Rounds. January 5, 2011. Nicotine and Fat Redistribution: The Key Link Between Cigarette Smoking and Heart Disease/Diabetes?
Charles Drew University MBRS PRIDE lecture series. April 5, 2011 “Grantsmanship and Grantwriting,” Pt 5. How to strategize for the most successful grant.
Virginia Commonwealth University Biochemistry and Molecular Biology Conference, May 9, 2011. Nicotine, Non-alcoholic fatty liver disease and Insulin Resistance: The Key Link Between Cigarette Smoking and Heart Disease/Diabetes?
MLK Ambulatory Care Clinic Medicine Grand Rounds. July 15, 2011. Addison’s disease: A presidential perspective.
Harbor-UCLA-Medical Center, Endocrine Clinical Conference. August 3, 2011. Addison’s disease: A presidential perspective.
Charles Drew University MBRS PRIDE lecture series. August 4, 2011 “How to Listen” with Dr. Keith Norris.
Charles Drew University MBRS PRIDE lecture series. August 30, 2011 “Scientific Manuscript Writing”.
Charles Drew University 4th year medical student lecture. October 3, 2011 “Scientific Manuscript Writing”.
Harbor-UCLA-Medical Center Endocrine Research Conference, October 5, 2011. Nicotine and Fat Redestribution: The Key Link Between Cigarette Smoking and Heart Disease/Diabetes?
Charles Drew University 4th year medical student lecture. October 10, 2011 “Scientific Manuscript Writing”.
University of Arizona School of Medicine, Noon Research Conference. November 14, 2011. Nicotine, Non-alcoholic fatty liver disease and Insulin Resistance: The Key Link Between Cigarette Smoking and Heart Disease/Diabetes?
MLK Ambulatory Care Clinic Medicine Grand Rounds. November 18, 2011. Thyroid, adrenal and pituitary incidentalomas: What to do… and what not to do?
Pfizer Informational Program. December 5, 2011. The Role of a GH Receptor Antagonist (GHRa) in the Treatment of Patients With Acromegaly
Charles Drew University, Cancer Cluster Research Conference. December 18, 2011. Nicotine, Non-alcoholic fatty liver disease and Insulin Resistance: The Key Link Between Cigarette Smoking and Heart Disease/Diabetes?
MLK Ambulatory Care Clinic Staff Meeting. April 20, 2012. How to Live to 100, Part 1.
Charles Drew University Endocrinology Journal Club. May 15, 2012. Nicotine Induces Negative Energy Balance Through Hypothalamic AMP-Activated Protein Kinase
MLK Ambulatory Care Clinic Staff Meeting. May 18, 2012. How to Live to 100, Part 2.
Endocrine Society Diabetes Press Conference. June 24, 2012. Multivariate Data Analysis from the National Health and Nutrition Examination Survey (NHANES), 2001-2006 Shows that Second-hand Smoke is Associated with Both Obesity and Diabetes Mellitus.
Harbor-UCLA-Medical Center, Endocrine Clinical Conference. October 24, 2012. An update on Cushing’s Syndrome.
Charles Drew University special lecture series. January 10, 2013 SCORE grants-2013
Charles Drew University Seminars in Addiction Research. April 10, 2013. Metabolic Effects of Nicotine.
Charles Drew University Cancer Journal Club. April 15, 2013. Effect of nicotine on body composition in mice/Additive effects of nicotine and high fat diet on hepatic steatosis in male mice
MAGIC Foundation’s Adult Convention (Las Vegas) April 21, 2013 The Ins and Outs of Pituitary Hormone Replacement.
MAGIC Foundation’s Adult Convention (Las Vegas) April 21, 2013 Nuances of Cushing’s Syndrome
MAGIC Foundation’s Adult Convention (Las Vegas) April 21, 2013 Grill the professor- pituitary hormone replacement including GH.
Charles Drew University MPH Student Drug Addiction Research Colloquium. April 22, 2013. Metabolic Effects of nicotine.
Charles Drew University-MLK-MACC Quality Improvement CME Series April 26, 2013 Increasing BMI: A big problem needing a new approach.
California State University-Dominguez Hills BIO 491-Seminar in Biological Research. May 2, 2013. Nicotine Plus a High Fat Diet: A Deadly Combo Leading to Hepatic and Muscle Steatosis.
Pfizer Informational Program. July 17, 2013. Genotropin: A Treatment for Adult Growth Hormone Deficiency
Charles R. Drew University-MLK-MACC Internal Medicine Meeting July 22, 2013 Increasing BMI: A big problem needing a new approach.
Charles R. Drew University-MLK-MACC Internal Medicine Grand Rounds August 16, 2013 An unusual case of hypopituitarism presenting with osteoporosis and erectile dysfunction.
Charles R. Drew University Cross-Disciplinary Lecture August 21, 2013 Increasing BMI: A big problem needing a new approach.
Charles R. Drew University 3^rd year medical students meet and greet, August 27, 2013
CERP Faculty and Community Partners Meetings December 19, 2013 Obesity group visits: An innovative program to deliver obesity services at DHS facilities.
Ohio State University Endocrinology Research Conference March 24, 2014 Effects of nicotine on hepatic steatosis, weight-loss and insulin resistance.
Medical University of South Carolina Endocrinology Research Conference July 28, 2014 Effects of nicotine on hepatic steatosis, weight-loss and insulin resistance.
University of Cincinnati Endocrinology, Diabetes and Metabolism Special Conference August 25, 2014 Effects of nicotine on hepatic steatosis, weight-loss and insulin resistance.
California-AACE 14th Annual Meeting & Symposium, September 21, 2014. Adrenal insufficiency
1^st annual DHS diabetes day December 3, 2014. Overview of the day and introduction to the Endocrinology Workgroup.
1^st annual DHS diabetes day December 3, 2014. Group visits, a new model for effective treatment: Obesity and Diabetes
Charles Drew University AXIS Professional and Development and Pilot Core lecture series. January 15, 2015 MBRS and CTSI-KL2 grant submissions.
Charles Drew University AXIS Professional and Development and Pilot Core lecture series. January 22, 2015 How to Make Your Grant More Hypothesis Driven.
BMH-BJ Synagogue, Denver, CO, Saturday afternoon lecture series June 27, 2015 How to Live to 120 and make it in one piece!
MAGIC Foundation’s Adult Convention (Chicago) July 12, 2015 Everything You Wanted to Know About Cushing’s Syndrome
MAGIC Foundation’s Adult Convention (Chicago) July 12, 2015 Everything You Wanted to Know About Pituitary Hormone Replacement.
Charles Drew University AXIS Professional and Development and Pilot Core lecture series. August 6, 2015 Preparation of your Biosketch and CV.
Charles Drew University Cardiometabolic Cluster Research In Progress August 15, 2015 Effects of Coke, Sugar Coke and Diet Coke Plus Nicotine on Body Weight, Food Intake and Hepatic Steatosis.
Charles Drew University Health Sciences Library Special Lecture November 4, 2015 Nicotine: Vice or Virtue.
Tirosint Speakers Program November 4, 2015 Tirosint: Challenges of T4 Therapy.
Harbor-UCLA-Medical Center, Internal Medicine Grand Rounds. February 9 2016 Nicotine: Vice or Virtue.
The Medical Center of Aurora Medicine Grand Rounds February 15 2016 Obesity: A big problem needing a new solution.
MAGIC Foundation’s Adult Convention (Chicago) July 22, 2016 What to do when Cushing’s symptoms return?
MAGIC Foundation’s Adult Convention (Chicago) July 22, 2016 Familial Cushing’s: Could it be genetic?
MAGIC Foundation’s Adult Convention (Chicago) July 22, 2016 Pituitary Hormones and weight and sleep
Master of Science in Biomedical Sciences Program September 21, 2016. Research Opportunities in the Friedman lab.
Obesity Medicine Association: Overcoming Obesity 2016 September 23, 2016. Metabolic Effects of Smoking Cessation and Implications for Prevention of Weight Gain (keynote speaker).
Harbor-UCLA-Medical Center, Translational Endocrinology Conference. November 9, 2016 Nicotine and Body Weight
Southern California American Diabetes Association Research Symposium November 30, 2016 Effects of Nicotine on Glycemic Parameters and Body Weight
Pfizer Speakers Bureau at Harbor-UCLA-Medical Center. December 8, 2016, Acromegaly Management: Disease and Therapy Overview
BMH-BJ Synagogue, Denver, CO, Saturday afternoon lecture series February 18, 2017 How to Live to 120 part 2
Charles Drew University Dr. M. Alfred Haynes Lecture Series March 1, 2017 “California’s Diabetes Crisis” and What We are Doing About it at CDU
Endocrine Division/ Cardio-Metabolic Cluster Journal Club April 20, 2017 Impact of the Berkeley and Mexico Excise Taxes on Sugar-Sweetened Beverage Consumption
BMH-BJ Synagogue, Denver, CO, Saturday afternoon lecture series May 27, 2017 How to Live to 120 part 3
MLK Outpatient Center Journal Club July 7, 2017 Effectiveness of Diabetes Interventions in the Patient-Centered Medical Home
Master of Science in Biomedical Sciences Program September 13, 2017. Research Opportunities in the Friedman lab.
Harbor-UCLA-Medical Center, Translational Endocrinology Conference. November 15, 2017 Obesity: A Big problem in Search of a New Solution
BMH-BJ Synagogue, Denver, CO, Saturday afternoon lecture series November 25, 2017 Sleep, stress, and social jet lag, the three evil Ss

Media Appearances

Fitness Talk with Dr. Fitness (Lance Drayer)-KFYI Radio (Phoenix, AZ)- November 12, 2000 Insulin Resistance and Stress.
Fitness Talk with Dr. Fitness (Lance Drayer)-KFYI Radio (Phoenix, AZ)- May 13, 2001 Insulin Resistance and Diet for Women.
Power Surge Internet Chat: Everything you need to know about hormone imbalances June 28, 2001
CBS National News (The Early Show with Bryant Gumbel and Jane Clayson) http://cbsnews.com/earlyshow/healthwatch/healthnews/20020227hw_cushings.shtml, February 27, 2002, Cushing’s Disease
KPHO TV Evening News (Phoenix, AZ) February 26, 2002 Cushing’s Disease.
Los Angeles Times op/ed article in the “Voices. A Forum for Community Issues” Section. A Guided Tour of King/Drew , (co-authors, S. Bhasin and M. Davidson) Sept. 20, 2003, p. B25.
Power Surge Internet Chat: Cushing’s Syndrome November 11, 2003.
Power Surge Internet Chat: Cushing’s Syndrome March 2, 2004.
Quoted in “The Mysterious Malaise” by Lynn Ginsburg, Alternative Medicine, September 2004, 89-91, 122-126.
KCBS News interview May 16, 2005 Doctors speak out about King-Drew Medical Center
KNBC News interview May 16, 2005 Doctors speak out about King-Drew Medical Center
Quoted in “The Exhaustion Epidemic” by Joe Hooper, Elle, February 2006, 190-192.
Quoted in “New Thyroid Cure” by Melanie Haiken, Health, June 2006, 102-107, 122-126.
Quoted in Los Angeles Times op/ed article “New President Vows to Expand Drew University’s Ambitions” October 14, 2006, B3.
Quoted in “Low-Revving Motor” by Marissa Candela, Energy Times, October 2007, 12-13.
Quoted in “Blame It On the Thyroid” by Winnie Yu, Weight Watchers Magazine, September/October 2007, 44,46.
National Geographic Channel, September 18, 2007, “The Science of Obesity” 15-minute segment on Cushing’s Syndrome
Quoted in “Gaining Weight? Feeling Depressed? Tired All The Time?” by Winnie Yu, Better Health and Living, January 2008, http://www.betterhealthandliving.com/articles/gaining_weight_feeling_depressed_tired_all_the_time/.
Cushings-Help Chat: Cushing’s Syndrome January 29, 2009. http://www.blogtalkradio.com/CushingsHelp/2009/01/30/Interview-with-Dr-Ted-Friedman-DR-F
Cushings-Help Chat: Cushing’s Syndrome March 12, 2009. http://www.blogtalkradio.com/cushingshelp/2009/03/13/second-interview-with-dr-ted-friedman-dr-f
ENDO 09 abstract, “The Mechanisms Of Nicotine-Induced Glucose Intolerance: Role In The High Prevalence Of Cardiovascular Disease In Smokers,” was picked by the Endocrine Society as being particularly newsworthy, and was singled it out for special media attention in the Endocrine Society’s annual Research Summaries Book (RSB). This press release was picked by multiple national and international news reports and was widely cited on the internet.
Cushings-Help Chat: Cushing’s Syndrome February 13, 2011. http://www.blogtalkradio.com/cushingshelp/2011/02/14/dr-ted-friedman-returns-for-his-third-interview OR http://itunes.apple.com/us/podcast/dr-ted-friedman-returns-for/id350591438?i=91275701
Interview with Mary Shomon on potassium iodide and the Japanese nuclear reactor, March 16, 2011 at http://thyroid.about.com/od/radiationnuclearexposure/a/Iodine-Thyroid-Japanese-Radiation.
Quoted in Tehran Times “5 Reasons you are losing your hair” May 19, 2011, News Code: TTime- 239919
Quoted in Los Angeles Times “Extreme Makeover: Weight Loss Edition” June 27, 2011, http://www.latimes.com/health/la-he-unreal-extreme-makeover-20110627,0,7438977.column
Los Angeles Times letter to the editor “College: A Smart Choice” August 29, 2011, http://www.latimes.com/news/opinion/letters/la-le-0822-monday-20110822,0,2346567.story?page=3.
Quoted in Women’s Day, Nov 1, 2011 The Surprising Reason You’re Always Tired http://www.womansday.com/health-fitness/conditions-diseases/the-surprising-reason-youre-always-tired-124243
Quoted in Bottom Line Personal, March 15, 2012 To make your hypothyroid medication more effective. p. 12
Cushings-Help Chat: Medical Treatment for Cushing’s Syndrome March 11, 2012. http://www.blogtalkradio.com/cushingshelp/2012/03/13/questions-about-medical-therapies-for-cushings OR http://itunes.apple.com/podcast/cushingshelp-cushie-chats/id350591438.
Article in Bottom Line Personal, July 1, 2012 The Surprising Cause of Fatigue Even Doctors Overlook. p. 9-11.
ENDO 12 abstract, “Multivariate Data Analysis from the National Health and Nutrition Examination Survey (NHANES), 2001-2006 Shows that Second-hand Smoke is Associated with Both Obesity and Diabetes Mellitus” was picked by the Endocrine Society as being particularly newsworthy, and was singled it out for special media attention in our annual Research Summaries Book (RSB). This press release was picked by multiple national and international news reports and was widely cited on the internet.
Featured in HealthDay, News for Healthier Living June 24, 2012. Secondhand smoke linked to raised diabetes risk https://consumer.healthday.com/diabetes-information-10/misc-diabetes-news-181/secondhand-smoke-linked-to-raised-diabetes-risk- 665888.html
Featured in Healio Endocrine Today August 2012. NHANES: Secondhand smoke linked to obesity, diabetes https://www.healio.com/endocrinology/diabetes/news/print/endocrine-today/%7B7f95dce9-b4ad-4f74-89fd-59a4fbf540fc%7D/nhanes-secondhand-smoke-linked-to-obesity-diabetes
Featured in Los Angeles Times “Group meetings turn doctor visits inside out” September 17, 2013, p. 1, http://www.latimes.com/local/la-me-group-doctor-visits-20130917,0,5085574,full.story
Interviewed on Univision Evening News (Los Angeles Channel 34) October 10, 2013, Obesity Group Visits, http://losangeles.univision.com/videos/video/2013-10-08/citas-medicas-en-grupo-un.
Pictured in Los Angeles Times “Diet and exercise alone are no cure for obesity, experts say” February 13, 2015, Science Now, http://www.latimes.com/science/sciencenow/la-sci-sn-eat-less-more-obesity-20150212-story.html
ENDO 15 abstract, “Metabolic Effects of Smokers Undergoing Smoking Cessation,” was picked by the Endocrine Society as being particularly newsworthy, and was singled it out for special media attention in the Endocrine Society’s annual Research Summaries Book (RSB). This press release was picked by multiple national and international news reports and was widely cited on the Internet. An interview with Dr. Friedman regarding our findings is available at http://www.hcplive.com/conferences/endo-2015/Weighing-the-Risks-of-Quitting-Smoking-and-Obesity.
ENDO 15 abstract, “Obesity group visits: a new approach for a big problem of inner city obesity”. An interview with Dr. Friedman regarding our findings is available at http://www.hcplive.com/conferences/endo-2015/Taking-Obesity-Treatment-Into-a-Group-Setting.
Featured in Redbookmag.com “7 Foods That Balance Your Sex Hormones” http://www.redbookmag.com/body/healthy-eating/g2844/foods-balance-sex-hormones/
Interviewed on Channel 7 News (Los Angeles Channel 7) August 10, 2015, Dancing With Doctors? A New Program For Obese Patients, http://abc7.com/health/dancing-with-doctors-a-new-program-for-obese-patients/919515/
Interviewed on Univision Evening News (Los Angeles Channel 34) August 10, 2015, Diabetes fights to the sound of the Zumba http://t.co/HrerBhQdej/s/Uq0P
Quoted in WebMD, Nov 1, 2015 Why You Are So Tired, 10 Causes of fatigue. http://www.webmd.com/women/guide/why-so-tired-10-causes-fatigue.
RadioMD podcast, July 7, 2016, Stress, Sleep Deprivation & Social Jet Lag http://radiomd.com/show/her/item/32375-stress-sleep-deprivation-social-jet-lag
Los Angeles Times letter to the editor. October 26, 2016 Soda taxes work. We should have more of them. http://www.latimes.com/opinion/readersreact/la-ol-le-soda-taxes-20161026-snap-story.html
Interview with HollywoodLife on Mary Tyler Moore and Diabetes, January 25, 2017. http://hollywoodlife.com/2017/01/25/mary-tyler-moore-death-caused-by-diabetes-expert-speaks/
Interview with HollywoodLife on Mischa Barton and her hospitalization January 27, 2017. http://hollywoodlife.com/2017/01/27/how-long-will-mischa-barton-be-hospitalized-hospital-stay-breakdown/
Featured in Washington Post, April 5, 2017 Is adrenal fatigue real? Forget the label and treat the stress. https://www.washingtonpost.com/lifestyle/wellness/is-adrenal-fatigue-real-forget-the-label-and-treat-the-stress/2017/04/04/6952b2b6-1889-11e7-9887-1a5314b56a08_story.html?utm_term=.946ed6fdc637#comments
Featured in Endocrine News August 2017 Innocent Bystanders. https://endocrinenews.endocrine.org/innocent-bystanders/
Quoted in Endocrine News September 2017 The Myth of Adrenal Fatigue. https://endocrinenews.endocrine.org/myth-adrenal-fatigue/

Conferences Organized

Substance Abuse Research Day at The Charles Drew University July 28, 2005.

2^nd annual Substance Abuse Research Day at The Charles Drew University August 10, 2006.

3rd annual Substance Abuse Research Day at The Charles Drew University September 7, 2007

4th annual Substance Abuse Research Day at The Charles Drew University September 26, 2008

Legislative Black Caucus Foundation: Expanding Healthcare Opportunities For Underserved Communities (part of LBCF business and professional conference) May 16, 2009

5th annual Substance Abuse Research Day at The Charles Drew University July 31, 2009

6th annual Substance Abuse Research Day at The Charles Drew University August 13, 2010

How to Be a Great Mentor Symposium at The Charles Drew University January 18, 2011

1^st Obesity Research Day at The Charles Drew University March 25, 2011

7th Substance Abuse Research Day at Charles R. Drew University August 17, 2012

8th Substance Abuse Research Day at Charles R. Drew University June 14, 2013

9th Substance Abuse Research Day at Charles R. Drew University September 9, 2014

1^st annual Los Angeles County DHS Diabetes Day, December 3, 2014.

10th Substance Abuse Research Day at Charles R. Drew University August 7, 2015

2nd annual Los Angeles County DHS Diabetes Day, November 23, 2015

11th Substance Abuse Research Day at Charles R. Drew University August 5, 2016

3rd annual Los Angeles County DHS Diabetes Day, November 7, 2016

Southern California American Diabetes Association Research Symposium November 30, 2016 (co-organizer)

12th Substance Abuse Research Day at Charles R. Drew University September 15, 2017

4th annual Los Angeles County DHS Diabetes Day, October 2, 2017

Conferences Moderated

California Legislative Black Caucus Foundation: Diabetes/Obesity Health Summit December 5, 2007

California Legislative Black Caucus Foundation: Health Summit on Diabetes and Obesity October 14, 2009

Publications & Bibliography

Books

Friedman, T.C. and Yu, W. (2007) The Everything Health Guide to Thyroid Disease. Adams Media, Avon, MA
Friedman, T.C. and Scherer, W.Y. (2011) The Everything Guide to Thyroid Disease, 2^nd Adams Media, Avon, MA

Chapters

Azaryan, A.V., Friedman, T.C., Cawley, N.X. and Loh, Y.P. (1995) Characteristics of YAP3, A New Prohormone Processing Aspartic Protease from S. Cerevisiae. in Aspartic Proteinases: Structure, Function, Biology, and Biomedical Implications (Takahashi, K., ed.) Plenum Press, New York, pp. 569-572.
Loh, Y.P., Cawley, N.X., Friedman, T.C. and Pu, L-P. (1995) Yeast and Mammalian Paired Basic Residue-Specific Aspartic Proteases in Prohormone Conversion in Aspartic Proteinases: Structure, Function, Biology, and Biomedical Implications (Takahashi, K., ed.) Plenum Press, New York, pp. 519-527.
Friedman, T.C. and Braunstein, G.D. (1997) Adrenal Gland in Cecil Essentials of Medicine, 4th edition (Andreoli, T.E., Bennett, J.C., Carpenter, C.C.J., and Plum, F., eds.) W.B. Saunders, Philadelphia, pp. 497-508.
Herman-Bonert, V., Friedman, T.C. and Braunstein, G.D. (1997) The Thyroid Gland in Cecil Essentials of Medicine, 4th edition (Andreoli, T.E., Bennett, J.C., Carpenter, C.C.J., and Plum, F., eds.) W.B. Saunders, Philadelphia, pp. 487-496.
Friedman, T.C. (2001) The Adrenal Gland in Cecil Essentials of Medicine, 5th edition (Carpenter, C.C.J., Griggs, R.C. and Loscalzo, J., eds.) W.B. Saunders, Philadelphia, pp. 564-574.
Herman-Bonert, V. and Friedman, T.C. (2001) The Thyroid Gland in Cecil Essentials of Medicine, 5th edition (Carpenter, C.C.J., Griggs, R.C. and Loscalzo, J., eds.) W.B. Saunders, Philadelphia, pp. 555-563.
Friedman, T.C. (2001) Pseudo-Cushing Syndrome in Contemporary Endocrinology: Adrenal Disorders (Margioris A.N. and Chrousos, G.P., eds.) Humana Press, Totowa, NJ, pp. 203-218.
Friedman, T. (2001) Pseudo-Cushing’s in Pituitary Patient Resources Guide, 3rd edition (Ezzat, S. and Knutzen, R. eds.) Pituitary Network Association, Thousand Oaks, CA, pp. 53-60.
Friedman, T.C. (2004) The Adrenal Gland in Cecil Essentials of Medicine, 6th edition (Carpenter, C.C.J., Griggs, R.C. and Loscalzo, J., eds.) W.B. Saunders, Philadelphia, 603-614.
Herman-Bonert, V. and Friedman, T.C. (2004) The Thyroid Gland in Cecil Essentials of Medicine, 6th edition (Carpenter, C.C.J., Griggs, R.C. and Loscalzo, J., eds.) W.B. Saunders, Philadelphia, 593-602.
Friedman, T.C. and Cool, D.R. (2004) Prohormones in The Encyclopedia of Endocrinology and Endocrine Diseases, Martini, L. (ed.) Elsevier Academic Press, San Diego, v.4, 91-98.
Friedman, T.C. (2007) The Adrenal Gland in Andreoli and Carpenter’s Cecil Essentials of Medicine, 7th edition (Carpenter, C.C.J., Griggs, R.C. and Benjamin, I.J., eds.) Saunders Elsevier, Philadelphia, 657-669.
Friedman, T.C. and Herman-Bonert, V. (2007) The Thyroid Gland in Andreoli and Carpenter’s Cecil Essentials of Medicine, 7th edition (Carpenter, C.C.J., Griggs, R.C. and Benjamin, I.J., eds.) Saunders Elsevier, Philadelphia, 647-656.
Friedman, T.C. (2008) Neuroendocrine Aspects of Skull Base Surgery in Endoscopic Skull Base Surgery (Shahinian, H.K., ed.) Humana Press, Totowa, NJ, 11-19.
Friedman, T.C. (2010) The Adrenal Gland in Andreoli and Carpenter’s Cecil Essentials of Medicine, 8th edition (Andreoli, T.E., Benjamin, I.J., Griggs, R.C. and Wing, E.J., eds.) Saunders Elsevier, Philadelphia, 679-690.
Herman-Bonert, V.S. and Friedman, T.C. (2010) The Thyroid Gland in Andreoli and Carpenter’s Cecil Essentials of Medicine, 8th edition (Andreoli, T.E., Benjamin, I.J., Griggs, R.C. and Wing, E.J, eds.) Saunders Elsevier, Philadelphia, 670-679.
Friedman, T.C. (2015) The Adrenal Gland in Andreoli and Carpenter’s Cecil Essentials of Medicine, 9th edition (Benjamin, I.J., Griggs, R.C., Wing, E.J., Fitz, J.G. eds.) Saunders Elsevier, Philadelphia, 642-651
Friedman, T.C. (2015) The Thyroid Gland in Andreoli and Carpenter’s Cecil Essentials of Medicine, 9th edition (Benjamin, I.J., Griggs, R.C. and Wing, E.J, Fitz, J.G. eds.) Saunders Elsevier, Philadelphia, 633-641

LETTERS TO THE EDITOR

Friedman, T.C., and Chrousos, G.P. (1993) Transsphenoidal Resection in Cushing’s Disease: Definition of Success (letter). Clin. Endocrinol. 39:701.
Friedman, T.C., and Papanicolaou, D. (1998) High Urinary Free Cortisol Excretion in a Patient with Psychogenic Polydipsia (letter). J. Clin. Endocrinol. Metab. 83:3378.
Friedman, T.C., Adesanya, A. and Poland, R.E. (1999) Low-Dose Hydrocortisone Treatment Of Chronic Fatigue Syndrome: A Randomized Controlled Trial (letter). JAMA 281:1888.
Friedman, T.C., Echeverry, D. and Poland, R.E. (2001) Orthostatic Hypotension and Chronic Fatigue Syndrome: A Randomized Controlled Trial (letter). JAMA 285:1442-1443.
Padero, C., Friedman, T. Salehian, B. (2001) Comment on the Editorial “The role of Androgens in Women” (letter). J. Clin. Endocrinol. Metab. 86: 5091-2.
Friedman, T.C. (2004) Prolactinomas (letter) New Eng. J. Med, 350: 1054-1057. PMID: 14999121.

REVIEWS-PEER-REVIEWED

Crofford, L.J., Sano, H., Karalis, K., Webster, E.A., Friedman, T.C., Chrousos, G.P., Wilder, R.L. (1995) Local Expression of Corticotropin-Releasing Hormone in Inflammatory Arthritis. Ann. N.Y. Acad. Sci. 771:459-471.
Padero, C., Bhasin, S. Friedman, T.C. (2002) Androgen Supplementation in Older Women: Too Much Hype, Not Enough Data J. Am. Geriatr. Soc. 50:1131-1140. PMID: 12110078.
Friedman, T.C., Norris, K.C. (2002) The role of vitamin D hormone in mild to moderate chronic kidney disease. Trends Endocrinol Metab. 13:189-194. PMID: 12185664.
Vuong, C., Van Uum, S.H.H., O’Dell, L.E., Lutfy, K., Friedman, T.C., (2010) The Effects of Opioids and Opioid Analogues on Animal and Human Endocrine Systems. Endocrine Rev. 31:98-132. PMID: 19903933. PMCID: PMC2852206
Friedman, T.C., (2011) Vitamin D supplementation to prevent the progression of pre-diabetes to diabetes: Getting closer to a recommendation Translational Research. 158:273-5. PMID: 220005266 PMCID: PMC3918469
Tweed, J.O., Hsia, S.H., Lutfy, K., Friedman, T.C., (2012) The Endocrine Effects of Nicotine and Cigarette Smoke. Trends in Endocrinol. Metab. 23:334-42. PMID: 22561025, PMCID: PMC3389568
Harris, K.K., Zopey, M., Friedman, T.C., (2016) Metabolic Effects of Smoking Cessation. Nature Reviews Endocrinol. 12:299-308. PMID: 26939981. PMCID: PMC5021526.
Sinha-Hikim, A.P., Sinha-Hikim, I., Friedman, T.C. (2017) Connection of nicotine to diet-induced obesity and nonalcoholic fatty liver disease: cellular and mechanistic insights. Front Endocrinol (Lausanne).2017 Feb 10;8:23. doi: 10.3389/fendo.2017.00023. eCollection 2017. PMID: 28239368, PMCID:PMC5300964

REVIEWS-NON-PEER REVIEWED:

Friedman, T.C., (1999) Pseudo Cushing’s. Network 8:16-18.
Friedman, T.C. and Kimball, C. (2003) Endocrine Causes of Chronic Fatigue: A review of Symptoms, Treatments. The CFIDS Chronicle, 16:5-7.

EXPERT OPINIONS-NON-PEER REVIEWED:

Friedman, T.C. (2013) Point/Counter: Are TZDs still useful? Endocrine Today, July 2013, p.11.

Research Papers

RESEARCH PAPERS (PEER-REVIEWED)

Friedman, T. C., Orlowski, M. and Wilk, S. (1984) Prolyl Endopeptidase: Inhibition in vivo by N-benzyloxycarbonyl-prolyl-prolinal. J. Neurochem. 42: 237-241. PMID: 6358414.
Friedman, T. C., Orlowski, M. and Wilk, S. (1984) Peptide-Degrading Enzymatic Activities in GH3 Cells and Rat Anterior Pituitary Homogenates. Endocrinology 114: 1407-1412. PMID: 6368204.
Friedman, T. C., Kline, T. B. and Wilk, S. (1985) 5-Oxoprolinal: Transition State Aldehyde Inhibition of Pyroglutamyl Peptide Hydrolase. Biochemistry 24: 3907-3913. PMID: 2864952.
Wilk, S., Friedman, T. C. and Kline, T. B. (1985) Pyroglutamyl Diazomethyl Ketone: Potent Inhibitor of Mammalian Pyroglutamyl Peptide Hydrolase. Biochem. Biophys. Res. Commun. 130: 662-668. PMID: 2862865.
Friedman, T. C. and Wilk, S. (1985) The Effects of Inhibitors of Prolyl Endopeptidase and Pyroglutamyl Peptide Hydrolase on TRH Degradation in Rat Serum. Biochem. Biophys. Res. Commun. 132: 787-794. PMID: 2865955.
Friedman, T. C., Davies, T. F. and Wilk, S. (1986) Evidence for Regulation of a TRH Degradation Pathway in GH3 Cells. Endocrinology 118: 562-566. PMID: 3080309.
Friedman, T. C., and Wilk, S. (1986) Delineation of a Particulate Thyrotropin-Releasing Hormone-Degrading Enzyme in Rat Brain by the Use of Specific Inhibitors of Prolyl Endopeptidase and Pyroglutamyl Peptide Hydrolase. J. Neurochem. 46: 1231-1239. PMID: 2869108.
Friedman, T. C. and Fulop, G. (1988) Disulfiram Use at Hospital-Based and Free-Standing Alcoholism Treatment Centers. J. Subst. Abuse Treatment 5:139-143. PMID: 3236387.
Friedman, T.C., Thomas, P.M., Fleisher, T.A., Feuillan, P., Parker, R. I., Cassorla, F. and Chrousos, G.P. (1991) Frequent Occurence of Asplenism and Gallstones in Patients with Autoimmune Polyglandular Disease Type I. Am. J. Med. 91:625-631. PMID: 1750432.
Estivariz, F.E., Friedman, T.C., Chikuma, T. and Loh, Y.P. (1992) Processing of Adrenocorticotropin by Two Proteases in Bovine Intermediate Lobe Secretory Vesicle Membranes: A Distinct, Acidic, Tetrabasic-Residue Specific, Calcium-Activated Serine Protease, and a PC2-like Enzyme. J. Biol. Chem. 267:7456-7463. PMID: 1313803.
Doppman, J.L., Gill, J.R. Jr., Miller, D.L., Chang, R., Gupta, R., Friedman, T.C., Choyke, P.L., Feurstein, I.M., Dwyer, A.J., Jicha, D.L., Walther, M.M., Norton, J.A. and Linehan, W.M. (1992) Distinction Between Hyperaldosteronism Due to Bilateral Hyperplasia and Unilateral Aldosteronoma: Reliability of CT. Radiology 184:677-682. PMID: 1509049.
Oerter, K.E., Friedman, T.C., Andersson H.C. and Cassorla, F.G. (1992) A Familial Syndrome of Endocrine and Neuroectodermal Failure. Am. J. Med Gen. 44:487-491. PMID: 1442893.
Mixson, A.J., Friedman, T.C., Katz, D.A., Feuerstein, I.M., Taubenberger, J.K., Colandrea J.M., Oldfield, E.H. and Weintraub, B.D. (1993) Thyrotropin-Secreting Pituitary Carcinoma. J. Clin. Endocrinol. Metab. 76:529-533. PMID: 8432799.
Azaryan, A.V., Wong, M., Friedman, T.C., Cawley, N.X., Estivariz, F.E., Chen, H.-C., and Loh, Y.P. (1993) Purification and Characterization of a Novel Yeast Aspartic Protease Encoded by the YAP3 Gene: Similarity to the Mammalian Proopiomelanocortin Converting Enzyme. J. Biol. Chem. 260:7194-7205. PMID: 8389368.
Crofford, L.J., Sano, H., Karalis, K., Friedman, T.C., Epps, H.R., Remmers, E.F., Mathem, P., Chrousos, G.P., and Wilder, R.L. (1993) Corticotropin-Releasing Hormone in Synovial Fluids and Tissues of Patients with Rheumatoid Arthritis and Osteoarthritis. J. Immunol. 151:1587-1596. PMID: 8335947.
Mastorakos, G., Webster, E.L., Friedman, T.C., and Chrousos, G.P. (1993) Immunoreactive Corticotropin Releasing Hormone (CRH) and its Binding Sites in the Rat Ovary. J. Clin. Invest. 92: 961-968. PMID: 8394389.
Bouzas, E.A., Mastorakos, G., Friedman, T.C., Scott, M.H., Chrousos, G.P., and Kaiser-Kupfer, M.I. (1993) Posterior Subscapsular Cataracts in Endogenous Cushing Syndrome: An Uncommon Manifestation. Invest. Ophthalmol. Vis. Sci. 34:3497-3500. PMID: 8258505.
Friedman, T.C., Chen, H.C., and Loh, Y.P. (1993) Generation of (1-37) and (1-38) Forms of Adrenocorticotropin By Mono- and Di-Peptidyl Serine Carboxypeptidase Activities in Bovine Pituitary Secretory Vesicles. Endocrinology 133:2951-2961. PMID: 824333.
Auchus, R.J., Mastorakos, G., Friedman, T.C., and Chrousos, G.P. (1994) Corticotropin-Releasing Hormone Production by a Small Cell Lung Carcinoma in a Patient with ACTH-Dependent Cushing Syndrome. J. Endocrinol. Invest. 17:447-452. PMID: 7930390.
Friedman, T.C., Garcia-Borreguero, D., Hardwick, D., Akuete, C.N., Stambuk, M.K., Dorn, L.D., Starkman, M.N., Loh, Y.P., and Chrousos, G.P. (1994) Diurnal Rhythm of Plasma Delta Sleep-Inducing Peptide in Humans: Evidence for Positive Correlation with Body Temperature and Negative Correlation with Rapid Eye Movement and Slow Wave Sleep. J. Clin. Endocrinol. Metab. 78:1085-1089. PMID: 8175965.
Mastorakos, G., Scopa, C.D., Vryonidou, A., Friedman, T.C., Kattis, D., Phenekos, C., Merino, M.J., and Chrousos, G.P. (1994) Presence of Immunoreactive Corticotropin Releasing Hormone (CRH) in Normal and Polycystic Human Ovaries. J. Clin. Endocrinol. Metab. 79:1191-1197. PMID: 7525629.
Friedman, T.C., Loh, Y.P and Birch, N.P. (1994) In Vitro Processing of Pro-opiomelanocortin by Purified Recombinant PC1(SPC3). Endocrinology 135:854-862. PMID: 8070378.
Friedman, T.C., Garcia-Borreguero, D., Hardwick, D., Akuete, C.N., Doppman, J.L., Dorn, L.D., Yanovski, J.A., and Chrousos, G.P. (1994) Decreased Delta Sleep and Plasma Delta Sleep-Inducing Peptide Concentrations in Patients with Cushing Syndrome Neuroendocrinol. 60:626-634. PMID: 7700506.
Scopa, C.D., Mastorakos, G., Friedman, T.C., Melanchrinou, M., Merino, M.J., and Chrousos, G.P. (1994) Presence of Immunoreactive Corticotropin Releasing Hormone in Thyroid Lesions. Am. J. Pathol. 145:1159-1167. PMID: 7977646.
Pu, L-P., Hayes, W.P., Mill, J.F., Friedman, T.C., and Loh, Y.P. (1995) Expression of the Prohormone Convertase PC2 mRNA in Xenopus Laevis CNS: Co-localization with Pro-Thyrotropin-Releasing Hormone. J. Comp. Neuro. 354:71-86. PMID: 7615876.
Friedman, T.C., Gordon, V.M., Leppla, S.H., Klimpel, K.R., Birch, N.P. and Loh, Y.P. (1995) In Vitro Processing of Protective Antigen by Recombinant PC1(SPC3) and Bovine Intermediate Lobe Secretory Vesicle Membranes. Arch. Biochem. Biophys. 316:5-13. PMID: 7840657.
Friedman, T.C., Yanovski, J.A., Jayasvasti, V., Yanovski, S.Z., Koenig, R.J., and Wilk, S. (1995) Pyroglutamyl peptidase II (“Thyroliberinase”) Activity in Human Serum: Influence of Weight and Thyroid Status. J. Clin. Endocrinol. Metab. 80:1086-1089. PMID: 7714073.
Friedman, T.C., Loh, Y.P., Cawley, N.X., Birch, N.P., , MCID, S.S., Jackson, I.M.D., and Nillni, E.A. (1995) Processing of Pro-TRH by Bovine Intermediate Lobe Secretory Vesicle Membrane PC1 and PC2 Enzymes. Endocrinology 136:4462-4472. PMID: 7664666.
Mastorakos, G., Bouzas, E.A., Silver, P.B., Friedman, T.C., Chan, C-C., Caspi, R.R., and Chrousos, G.P. (1995) Immune Corticotropin-Releasing Hormone is Present in the Eyes of and Promotes Experimental Autoimmune Uveoretinitis in Rodents. Endocrinology 136:4650-4658. PMID: 7684685.
Vgontzas, A.N., Friedman, T.C., Chrousos, G.P., Bixler, E.O., Vela-Bueno, A., and Kales, A. (1995) Delta Sleep-Inducing Peptide in Normals and in Sleep Apnea and Narcolepsy. Peptides 16:1153-1156. PMID: 8532601.
Dorn, L.D., Burgess, E.S., Dubbert, B., Simpson, S.-E., Friedman, T., Kling, M., Gold, P.W., and Chrousos, G.P. (1995) Psychopathology in Patients with Cushing Syndrome: Melancholic or “Atypical” Features. Clin. Endocrinol. 43:433-442. PMID: 7586617.
Nillni, E.A., Friedman, T.C., Todd, R.B., Birch, N.P. Loh, Y.P., and Jackson, I.M.D. (1995) ProTRH Processing by PC1. J. Neurochem. 65:2462-2472. PMID: 7595540.
Friedman, T.C. and Yanovski, J.A. (1995) Morning Plasma Free Cortisol: Inability to Distinguish Patients with Mild Cushing Syndrome from Patients with Pseudo-Cushing States. J. Endocrinol. Invest. 18:696-701. PMID: 8719300.
Friedman, T.C., Cool, D.R., Jayasvasti, V., Louie, D., and Loh. Y.P. (1996) Processing of Pro-opiomelanocortin in GH3 Cells: Inhibition by Prohormone Convertase 2 (PC2) Antisense mRNA. Mol. Cell. Endocrinol. 116:89-96. PMID: 8822269.
Mastorakos, G., Scopa, C.D., Kao, L.C., Vryonidou, A., Friedman, T.C., Kattis, D., Phenekos, C., Rabin, D., and Chrousos, G.P. (1996) Presence of Immunoreactive Corticotropin Releasing Hormone Human Endometrium. J. Clin. Endocrinol. Metab. 81:1046-1050. PMID: 8772574.
Kalogeras, K.T., Nieman, L.K., Friedman, T.C., Doppman, J.L., Cutler, Jr., G.B., Chrousos, G.P., Wilder, R.L., Gold, P.W., and Yanovski, J.A. (1996) Inferior Petrosal Sinus Sampling in Healthy Human Subjects Reveals a Unilateral Corticotropin-releasing Hormone-induced Arginine Vasopressin Release Associated with Ipsilaterally Lateralized Adrenocorticotropin Secretion. J. Clin. Invest. 97:2045-2050. PMID: 8621793.
Friedman, T.C., Yanovski, J.A., Nieman, L.K., Doppman, J.L., Cutler, Jr., G.B., Oldfield, E.H., Gold, P.M., Chrousos, G.P., and Kalogeras, K.T. (1996) Inferior Petrosal Sinus Arginine Vasopressin Concentrations in Normal Volunteers and Patients with Cushing’s Disease. J. Clin. Endocrinol. Metab. 81:3068-3072. PMID: 8768876.
Yanovski, J.A., Yanovski, S.Z., Friedman, T.C., Loh, Y.P., Jayasvasti, V., Cutler, Jr., G.B., and Chrousos, G.P. (1996) Etiology of the Differences in Corticotropin-Releasing Hormone-Induced ACTH Secretion of Black and White Women. J. Clin. Endocrinol. Metab. 81:3307-3311. PMID: 8784088.
Friedman, T.C., Mastorakos, G., Bouzas, E.A., Newman, T.D., Mullen, N.M., Horton, E.G., Costello, R., Papadopoulos, N.M., and Chrousos, G.P. (1996) Carbohydrate and Lipid Metabolism in Endogenous Hypercortisolism: Shared Features with Metabolic Syndrome X and NIDDM. Endocrine J. 43:645-655. PMID: 9075609.
Dorn, L.D., Burgess, E.S., Friedman, T., Gold, P.W., and Chrousos, G.P. (1997) The Longitudinal Course of Psychopathology in Cushing’s Syndrome after Correction of Hypercortisolism. J. Clin. Endocrinol. Metab. 82:912-919. PMID: 9062506.
Taymans, S.E., DeVries, A.C., DeVries, M.B., Nelson, R.J., Friedman, T.C., Castro, M., Detera-Wadleigh, S., Carter, C.S., and Chrousos, G.P. (1997) The Prairie Vole (Microtus Ochrogaster) as a Model of Glucocorticoid Resistance. Gen. Comp. Endocrinol. 106:48-61. PMID: 929465.
Yanovski, J.A., Friedman, T.C., Nieman, L.K., Chrousos, G.P., Cutler, Jr., G.B., Doppman, J.L., and Kalogeras, K.T. (1997) Inferior Petrosal Sinus Arginine Vasopressin in Patients with Cushing Syndrome. Clin. Endocrinol. 47:199-206. PMID: 9302395.
Ting, P., Cushenberry, P.A., Friedman, T.C., and Loh, Y.P. (1997) Enhanced Brain Opioid Receptor Activity Precedes Blood-Brain Barrier Disruption. Acta Neurochir. (Suppl.) 70:250-253. PMID: 9416337.
Li, Q.-L., Yano, H., Ren, S.G., Li, X., Friedman, T.C., Melmed, S. (1997) Leukemia Inhibitory Factor (LIF) Modulates Pro-opiomelanocortin (POMC) Gene Regulation in Stably-Transfected AtT-20 Cells Over-Expressing LIF. Endocrine 7:325-330. PMID: 9657069.
Shimon, I., Yan, X., Magoffin, D.A., Friedman, T.C., and Melmed, S. (1998) Intact Leptin Receptor is Selectively Expressed in Human Fetal Pituitary and Pituitary Adenomas and Signals Human Fetal Pituitary Growth Hormone Secretion. J. Clin. Endocrinol. Metab. 83: 4059-4064. PMID: 9814492.
Yanovski, J.A., Miller, K.D., Kino, T., Friedman, T.C., Chrousos, G.P., Tsigos, C. and Falloon, J. (1999) Endocrine and Metabolic Evaluation of Human Immunodeficiency Virus-Infected Patients with Evidence of Protease Inhibitor-Associated Lipodystrophy. J. Clin. Endocrinol. Metab. 84:1925-1931. PMID: 10372688.
Li, Q.-L., Jansen, E., and Friedman, T.C. (1999) Regulation of Prohormone Convertase 1 (PC1) By gp130-Related Cytokines. Molecular and Cellular Endocrinology 158:143-152. PMID: 10630414.
Nie, Y., Nakashima, M., Brubaker, P.L., Li, Q.-L., Perfetti, R., Jansen, E., Zambre, Y., Pipeleers, D., and Friedman, T.C. (2000) Regulation of Pancreatic PC1 and PC2 Associated with Increased GLP-1 in Diabetic Rats. J. Clin. Invest. 105:955-965. PMID: 10749575.
Nawab, S.S., Miller, C.S., Dale, J.K., Greenberg, B.D., Friedman, T.C., Chrousos, G.P., Straus, S.E., and Rosenthal, N.E. (2000) Self-reported sensitivity to chemical exposures in five clinical populations and healthy controls. Psychiatry Res. 95:67-74. PMID: 10904124.
Li, Q.-L., Jansen, E., Brent, G.A., Naqvi, S., Wilber, J.F., and Friedman, T.C. (2000) Interactions Between the Prohormone Convertase 2 (PC2) Promoter and the Thyroid Hormone Receptor. Endocrinology. 141:3256-3266.PMID: 10965896.
Garcia-Borreguero, D., Wehr, T.A., Larrosa, O., Granizo, J.J., Hardwick, D., Chrousos, G.P., and Friedman, T.C. (2000) Glucocorticoid Replacement is Permissive for REM sleep and Sleep Consolidation in Patients with Adrenal Insufficiency. J. Clin. Endocrinol. Metab. 85:4201-4206. PMID: 11095454.
Li, Q.-L., Jansen, E., Brent, G.A., and Friedman, T.C. (2001) Regulation of Prohormone Convertase 1 (PC1) by Thyroid Hormone. Am J. Physiol. Endocrinology 280:E160-E170. PMID: 11120670.
Nakashima, M., Nie, Y., Li, Q.-L, and Friedman, T.C. (2001) Induction of Splenic Prohormone Convertases PC1 and PC2 in Diabetic Rats. Reg. Peptides 102:135-45. PMID: 11730986.
Li, Q.-L., Naqvi, S., Shen, X., Liu, Y.-J., Lindberg, I., and Friedman, T.C. (2003) Prohormone Convertase 2 (PC2) Enzymatic Activity and its Regulation in Endocrine Cells. Reg. Peptides. 110:197-205. PMID: 12573800.
Liu, Y.J., Nakagawa, Y., Wang, Y., Li, R.S., Li. X.J. Ohzeki, T., and Friedman, T.C. (2003) Leptin Activates Intracellular Corticosterone Production in the Liver of ob/ob Mice. Diabetes. 52:1409-1416. PMID: 12765951.
Shen, X., Li, Q.-L., Brent, G.A., and Friedman, T.C. (2004) Thyroid Hormone Regulation of Prohormone Convertase 1 (PC1): Characterization of Negative Thyroid Hormone Response Elements and Studies in Rat Brain. J. Mol. Endocrinol. 33:21-33. PMID: 15291740.
Wang, C., Swerdloff, R., Kipnes, M., Matsumoto, A. M., Dobs, A.S., Cunningham, G., Katznelson, L., Weber, T.J., Friedman, T.C., Snyder, P., Levine, H.L. (2004) New Testosterone Buccal System (Striant^Ô) Delivers Physiologic Testosterone Levels: Pharmacokinetics Study in Hypogonadal Men. J. Clin. Endocrinol. Metab. 89:3821-3829. PMID: 15292312.
Sanchez, V.C., Goldstein, J., Stuart, R.C., Hovanesian, V., Lihong, H., Münzberg, H., Friedman, T.C., Bjørbæk, C. and Nillni, E.A. (2004) Regulation of Hypothalamic Prohormone Convertases 1 and 2 by Leptin and Fasting, and Effects on Processing of ProThyrotropin Releasing Hormone. J. Clin. Invest. 114:357-369. PMID: 15286802.
Roy, R., and Friedman, T.C. (2004) Subclinical Adrenal Insufficiency-A Disease, Like Subclinical Hypothyroidism, Whose Time Has Come. EndoTrends 11 (3):14-15.
Shen, X., Li, Q.-L., Brent, G.A., and Friedman, T.C. (2005) Prohormone 2 (PC2) Regulation of regional expression in rat brain PC2 by thyroid hormone/characterization of novel negative thyroid hormone response elements in the PC2 promoter. Am. J. Physiol. Endocrinol. Metab. 288:E236-E245. PMID: 15585599.
Liu, Y.J., Nakagawa, Y., Wang, Y., Sakurai, R., Tripathi, P., Lutfy, K. and Friedman, T.C. (2005) Increased Glucocorticoid Receptor and 11b-hydroxysteroid Dehydrogenase Type 1 Expression in Hepatocytes May Contribute to the Phenotype of Type 2 Diabetes in db/db Mice. Diabetes 54:32-40. PMID: 15616008.
Choi, H.-J. H., Cornford, M., Sun, J., Wang, L. Sun, J. and Friedman, T.C. (2005) First reported case of acute Chagas’ disease presenting with a suprasellar mass and panhypopituitarism. Pituitary 7, 111-114. PMID: 15761661.
Hardiman, A., Friedman, T.C., Grunwald, Jr., W. C., Furuta, M., Steiner, D.F., and Cool, D.R. (2005) Endocrinomic profile of neurointermediate lobe pituitary prohormone processing in PC1/3- and PC2-Null mice using SELDI-TOF mass spectrometry J. Mol. Endo. 34:739-751. PMID: 15956344, PMCID: PMC4422198.
McGirr, R., Mugimba, A., Ejbick, C.E., Carter, D.E., Andrews, J.D., Nie, Y., Friedman, T.C., and Dhanvantari, S. (2005) Glucose Dependence of the Regulated Secretory Pathway in alphaTC1-6 Cells. Endocrinology 146:4514-4523. PMID: 15994347.
Friedman, T.C. and Shahinian, H. (2005) Bilateral Cerebral Aneurysms Impinging on the Pituitary. Pituitary (Images of the Pituitary) 7: 193-194. PMID: 16328569
Patel, P.M., Shahinian, H. Friedman, T.C. (2005) Cushing’s Disease is not necessarily a progressive and fatal disease: A case of Cushing’s Disease Documented Untreated for 26 years. Endocrinologist 15:343-344.
Marquez, M., Baliram, R., Gajawada, N., Friedman, T.C., and Lutfy, K. (2006) Differential involvement of enkephalins in analgesic tolerance, locomotor sensitization and conditioned place preference induced by morphine. Behavioral Neuroscience 120:10-15.PMID: 16492112.
Perello, M. Friedman, T. Paez-Espinosa, V., Shen, X., Stuart, R.C., and Nillni, E.A. (2006) Thyroid Hormones Selectively Regulate the Post-translational Processing of ProThyrotropin Releasing Hormone (ProTRH) in the Paraventricular Nucleus of the Hypothalamus. Endocrinology 147: 2705-2716. PMID: 16497799.
Friedman, T.C. (2006) An Update on the Overnight Dexamethasone Suppression Test for the Diagnosis of Cushing’s Syndrome: Limitations in Patients with Mild and/or Episodic Hypercortisolism. Experimental and Clinical Endocrinology and Diabetes 216: 356-360. PMID: 16915537.
Liu, Y., Yan, C., Wang, Y., Nakagawa, Y., Lutfy, K. and Friedman, T.C. (2006) Liver X receptor agonist T0901317 inhibition of glucocorticoid receptor expression in hepatocytes may contribute to the amelioration of diabetic syndrome in db/db Mice. Endocrinology 147:5061-5068. PMID: 16873540.
Lutfy, K., Brown, M.C., Nerio, N., Aimiuwu, O, Tran, B., Anghel, A., Friedman, T.C., (2006) Repeated Stress May Alter The Ability Of Nicotine To Activate The HPA Axis. J. Neurochem. 99: 1321-1327. PMID: 17064351.
Paez Espinosa, V., Ferrini, M., Shen, X., Lutfy, K., Nillni, E.A. and Friedman, T.C. (2007) Cellular co-localization and co-regulation between hypothalamic pro-TRH and prohormone convertases in hypothyroidism. Am. J. Physiol. Endocrinol. Metab. 292:E175-86, PMID: 16926379.
Sahasranam, P., Ballani, P. and Friedman, T.C. (2007) A “Natural Cure” for Acromegaly- Case Report and Literature Review of Pituitary Apoplexy. EndoTrends 14:7-9. PMID:
Friedman, T.C., Zuckerbraun, E., Lee, M.L., Kabil, M.S., Shahinian, H.K. (2007) Dynamic Pituitary MRI Has High Sensitivity and Specificity for the Diagnosis of Mild Cushing’s Syndrome and Should be Part of the Initial Workup. Hormone and Metabolic Research 39:451-456. PMID 17578763.
Sahasranam, P., Tran, M.T., Mohamed, H. and Friedman, T.C. (2007) Multiglandular parathyroid carcinoma: a case report and brief review Southern Medical Journal 100:841-844 PMID: 17713315.
Yuen, K.C.J., Cook, D,M., Sahasranam, P., Patel, P., Ghods, D.E., Shahinian, H.K., and Friedman, T.C. (2008) Prevalence of growth hormone deficiency in adults with non-secreting pituitary microadenomas and normal serum IGF-I levels Clin. Endocrinol (Oxf). 69:292-298. PMID: 18221393, PMCID: PMC2953553.
Liu, Y., Nakagawa, Y., Wang, Y., Liu, L., Du, H., Wang, W., Ren, X., Lutfy, K. and Friedman, T.C. (2008) Reduction of Hepatic Glucocorticoid Receptor and Hexose-6-Phosphate Dehydrogenase Expression Ameliorates Diet-Induced Obesity and Insulin Resistance in Mice. J. Molecular Endocrinology. 41:53-64. PMID: 18524870, PMCID: PMC2954685.
Pall, M.E., Lao, M.C., Patel, S.S., Lee, M.L., Ghods, D.E., Chandler, D.W. and Friedman, T.C. (2008) Testosterone and Bioavailable Testosterone Help to Distinguish Between Mild Cushing’s Syndrome and Polycystic Ovarian Syndrome. Hormone and Metabolic Research. 40:813-8. PMID: 18819057, PMCID: PMC2954657.
Espinosa, V.P., Liu, Y., Ferrini, M., Anghel, A., Nie, Y., Tripathi, P.V., Porche, R., Jansen, E., Lutfy, K, and Friedman, T.C. (2008) Differential Regulation of PC1/3, PC2 and phosphoryated CREB by short-term and long-term morphine treatment: Understanding the “Switch” to Opiate Addiction. Neurosci. 156:788-99. PMID: 18771713, PMCID: PMC2596639.
Fraser, L.A., Morrison, D., Morley-Forster, P., Paul, T.L., Tokmakejian, S., Nicholson, R.L., Bureau, Y., Friedman, T.C., Van Uum, S.H.M. (2009) Oral opioids for chronic non-cancer pain: higher prevalence of hypogonadism in men than in women. Experimental and Clinical Endocrinology and Diabetes. 17:38-43. PMID: 18523930, PMCID: PMC2953550.
Thomson, S., Koren, G., Fraser, L.A., Rieder, M.J., Friedman, T.C., Van Uum, S.H.M (2010) Hair Analysis Provides a Historical Record of Cortisol Levels in Cushing’s Syndrome. Experimental and Clinical Endocrinology and Diabetes. 118:133-8. PMID: 19609841, PMCID:PMC2945912.
Anghel, A., Jamieson, C.A.M, Ren, X., Young, J., Porche, R., Ozigbo, E., Ghods, D.E., Lee, M.L., Liu, Y., Lutfy, K., Friedman, T.C. (2010) Gene expression profiling reveals short-term and long-term morphine exposure regulates genes involved in food uptake in mice. Neuroscience 167:554-66. PMID: 20144693, PMCID: PMC2859888.
Kilimnik, G., Kim, A., Steiner, D.F., Friedman, T.C., and Hara, M (2010) Intraislet production of GLP-1 by activation of prohormone convertase 1/3 in pancreatic alpha-cells in mouse models of beta-cell regeneration. Islets 2:1-8 (on cover). PMCID: PMC2908328.
Chen, J., Patel, R., Friedman, T.C., and Jones, K.S. (2010) The Behavioral and Pharmacological Actions of NMDA Receptor Antagonism are Conserved in Zebrafish Larvae. Int J Comp Psychol. 23:82-90. PMCID: PMC3027073.
Friedman, T.C., Ghods, D.E., Zachery, L., Shayesteh, N., Seasholtz, S., Zuckerbraun, E., Shahinian, H.K., Lee, M.L., McCutcheon, I.E. (2010) High Prevalence of Normal Tests Assessing Hypercortisolism in Subjects with Mild and Episodic Cushing’s Syndrome Suggests that the Paradigm for Diagnosis and Exclusion of Cushing’s Syndrome Requires Multiple Testing. Hormone and Metabolic Research. 42: 874-881. PMID: 20803415. PMCID: PMC2978784.
Parikh, D., Hamid, A., Friedman, T.C., Nguyen, K., Tseng, A., Marquez, P., and Lutfy, K. (2011) Stress-induced analgesia and endogenous opioid peptides: the importance of stress duration.. European J. Pharmacol. 650:563-567. PMID: 21044625. PMCID: PMC3033575.
Wang, Y., Nakagawa, Y., Liu, Y., Wang, W., Ren, X., Anghel, A., Lutfy, K., Friedman, T.C., and Liu, Y. (2011) Tissue-specific dysregulation of hexose-6-phosphate dehydrogenase and glucose-6-phosphate transporter production in db/db mice as a model of type 2 diabetes. Diabetologia. 54:440-50. PMID: 21052977, PMCID: PMC3795617.
Mangubat, M., Lutfy, K., Lee, M.L., Pulido, L., Stout, D., Davis, R., Seasholtz, S., Sinha-Hikim, A., Sinha-Hikim, I., O’Dell, L., Lyzlov, A., Liu, Y., Friedman, T.C. (2012) Effect of nicotine on body composition in mice. Journal of Endocrinology. 212:317-326, PMID: 22138237, PMCID: PMC344240.
Rajavashisth, T.B., Shaheen, M., Pan, D., Sinha, S.K., Ortega, J. Friedman, T.C. (2012) Decreased Prevalence of Diabetes in Marijuana Users: Data from NHANES III. British Medical Journal Open 2:e000494. Print Feb 24 2012. PMID: 22368296. PMCID: PMC3289985.
Lutfy, K., Aimiuwu, O, Mangubat, M., Shin, C.S. Nerio, N., Gomez, R., Liu, Y., Friedman, T.C., (2012) Nicotine stimulates secretion of corticosterone via both CRH and AVP receptors. J. Neurochem. 120: 1108-1116. PMID: 22191943, PMCID: PMC3296864.
Nguyen, A.T., Marquez, P., Hamid, A., Kieffer, B., Friedman, T.C., and Lutfy, K. (2012). The rewarding action of acute cocaine is reduced in -endorphin deficient but not in mu opioid receptor knockout mice. Eur. J. Pharm., 686:50-4. PMID: 22575525, PMCID: PMC3367137.
Friedman, T.C., Sinha-Hikim, I., Parveen, M., Najjar, S.M., Mangubat, M., Shin, C.S., Lyzlov, Ivey, R., Shaheen, M., French, S.W., and Sinha Hikim, A., (2012) Additive effects of nicotine and high fat diet on hepatic steatosis in male mice. Endocrinology, 153: 5809-5820. PMID: 23093702, PMCID: PMC3512067
Davidson, M.B, Duran, P., Lee, M.L., Friedman, T.C. (2012) High Dose Vitamin D Supplementation in People with Pre-Diabetes and Hypovitaminosis D. Diabetes Care, 36:260–266. PMID: 23033239, PMCID: PMC3554269.
Du, H., Liu, Y., Wang, Y., Nakagawa, Y., Lyzlov, A., Lutfy, K., Friedman, T.C., Peng, X. and Liu, Y. (2013) Specific Reduction of G6PT May Contribute to Down-regulation of Hepatic 11β-HSD1 in Diabetic mice. J. Mol. Endocrinol. 50:167-178, PMID: 23267038, PMCID: PMC3763023.
Nie, Y., Ferrini, M.G., Liu, Y., Ren, X., Anghel, A., Paez Espinosa, E.V., Stuart, R.C., Lutfy, K, Nillni, E.A., and Friedman, T.C. (2013) Morphine treatment selectively regulates expression of rat pituitary POMC and the prohormone convertases PC1/3 and PC2. Peptides. 47:99-109. PMID: 23891651, PMCID: PMC3787842
Ren, X., Lutfy, K., Mangubat, M., Lee, M.L., Ferrini, M.G., Liu, Y., and Friedman, T.C. (2013) Effect of different morphine treatments leading to tolerance and dependence on phosphorylated CREB expression in different mouse brain regions. J. Obes. 2013:764742. doi: 10.1155/2013/764742. Epub 2013 Aug 29, PMID: 24073333, PMCID: PMC3773431
Liu, L., Nagashima, K., Yasuda, T., Liu, Y., Hu, H.R., He, G, Feng, B., Zhao, M., Zhuang, L., Zheng, T., Friedman T.C., Xiang, K. (2013) Mutations in KCNJ11 are associated with the development of autosomal dominant, early-onset type 2 diabetes. Diabetologia. 56:2609-18. PMID: 24018988
O’Dell, L.E., Natividad, L.A., Torres, I., Escalante, E., Roman, F., Valenzuela, V., Friedman, T.C., Tenayuca, J.M., Nazarian, A. (2014) Enhanced nicotine self-administration and suppressed dopamine systems in a rat model of diabetes, Addict. Biol., 19:1006-19, PMID: 23834715, PMCID: PMC3842417.
Huang, G., Basaria, S., Travison, T.G. Ho, M.H, Davda, M., Mazer, N.A., Miciek, R., Knapp, P.E, Zhang, A., Collins, L., Ursino, M., Appleman, A., Dzekov C., Stroh, H., Ouellette, M., Rundell, T., Baby, M., Bhatia, N.N., Khorram, O., Friedman, T., Storer, T.W., and Bhasin, S. (2014) Testosterone Dose-Response Relationships in Surgically Menopausal Women: Effects on Sexual Function, Body Composition, Muscle Performance and Physical Function in a Randomized Trial. Menopause. 21:612-23. PMID: 24281237, PMCID:PMC4701202.
Natividad, L.A., Torres, O.V., Friedman, T.C., O’Dell, L.E. (2013) Adolescence is a period of development characterized by short- and long-term vulnerability to the rewarding effects of nicotine and reduced sensitivity to the anorectic effects of this drug. Behav. Brain Res. 257:275-85. PMID: 24120402, PMCID: PMC3965174
Sinha-Hikim*, I., Friedman*, T.C., Shin, C.S., Ivey, R., Lee, D.L. and Sinha Hikim, A., (2014) Nicotine in combination with a high fat diet causes intramyocellular mitochondrial abnormalities in male mice. Endocrinology, 155:865–872. PMID: 24424058. PMCID: PMC3929732* Co 1^st authors

Wang, Y., Liu, Y., Du, H., Nagaoka, Y., Fan, W., Lutfy, K., Friedman, T.C., Jiang, M. and Liu, Y. (2014) Transgenic Overexpression of Hexose-6-Phosphate Dehydrogenase in Adipose Tissue Causes local Glucocorticoid Amplification and Lipolysis in Male Mice. Am. J. Physiol. Endocrinol. Metab.306:E543-51. PMID: 24381005. PMCID: PMC3948972
Ivey, R., Desai, M., Green, K. Sinha-Hikim, I., Friedman, T.C., Sinha-Hikim, A.P. (2014) Additive Effects of Nicotine and High-Fat Diet on Hepatocellular Apoptosis in Mice: Involvement of Caspase 2 and Inducible Nitric Oxide Synthase-Mediated Intrinsic Pathway Signaling. Hormone and Metabolic Research. 46: 568-573. PMID: 24830635, PMCID: PMC4327908.
Wang, Y., Yan, C., Liu, L., Wang, W., Du, H., Fan, W., Lutfy, K., Jiang, M., Friedman, T.C., and Liu, Y. (2015) 11ß-Hydroxysteroid Dehydrogenase Type 1 shRNA Ameliorates Glucocorticoid -Induced Insulin Resistance and Lipolysis in Mouse Abdominal Adipose Tissue. Am J Physiol Endocrinol Metab. 308:E84-95. PMID: 25389364. PMCID: PMC4281684
Sinha-Hikim, I., Duran, P., Shen, R., Lee, M.L., Friedman, T.C., Davidson, M.B. (2015) Effect of long term vitamin D supplementation on biomarkers of inflammation in Latino and African-American subjects with pre-diabetes and hypovitaminosis D. Hormone and Metabolic Research. 47:280-3. PMID: 25011019. PMCID: PMC4648252.
Teruya, S., Mojtahedzadeh, M. Doshi, M., Russell, K., Parker-Kelly, D. and Friedman, T.C. (2015) A Review of Programs, Components and Outcomes in Biomedical Research Faculty Development. International Journal of University Teaching and Faculty Development 4 223-236. PMCID: PMC4479301.
Mojtahedzadeh, M., Lee, M.L, Friedman, T.C. (2015) Continuation or discontinuation of pioglitazone when starting bedtime insulin in patients with poorly controlled type 2 diabetes in an inner-city population. Journal Diabetes Complications. 29:1248-52. PMID: 26215435. PMCID: PMC5014540.
Lutfy, K., Parikh, D., Lee, D.L., Liu, Y., Ferrini, M.G., Hamid, A., and Friedman, T.C. (2016) Prohormone convertase 2 (PC2) null mice have increased mu opioid receptor levels accompanied by enhanced morphine-induced antinociception, tolerance and dependence. Neuroscience. 329:318-25. PMID: 27208618 PMCID: PMC4933571.
Yan, C., Yang, H., Wang, Y., Dong, Y., Wu, Y., Wang, W., Ume, A., Lutfy, K., Friedman, T.C., Tian, S. and Liu, Y. (2016) Increased Glycogen Synthase Kinase-3β and Hexose-6-Phosphate Dehydrogenase Expression in Adipose Tissue May Contribute to Glucocorticoid-Induced Mouse Visceral Adiposity. Int. J. Obesity. 40: 1233-41. PMID: 27102048.PMCID: PMC4970937.
Sinha-Hikim, I., Friedman, T.C., Falz, M., Chalfant, V., Rea, I., Hasan, M.K. Espinoza-Derout, J., Lee, D.L., Sims, C., Tran, P., Mahahta, S.K., and Sinha-Hikim, A.P. (2017) Nicotine Plus a High-Fat Diet Triggers Cardiomyocyte Apoptosis in Male Mice By Inhibiting AMP-Activated Protein Kinase Independent of Fibroblast Growth Factor 21 and Silent Information Regulator 1. Cell and Tissue Research. 368:159-170
Kermah, D., Shaheen, M., Pan, D., Friedman, T.C. (2017) Association between Secondhand Smoke, Obesity and Diabetes: Data from the National Health and Nutrition Examination Survey (NHANES 1999-2010). BMJ Open, Diabetes Research and Care. Mar 21;5(1):e000324. doi: 10.1136/bmjdrc-2016-000324. eCollection 2017. PMID: 28405342, PMCID: PMC5372029.

RESEARCH PAPERS-PEER-REVIEWED (IN PRESS)

RESEARCH PAPERS-PEER-REVIEWED (SUBMITTED):

Brown, A.K., Sumerel, B., Shaba, W., Friedman, T.C., London, E.D., Mandelkern, M.S. (2018) Venturesomeness and PET measures of dopamine D2/D3 receptor availability. Journal of Psychiatry Research: Neuroimaging.
Hsia, S.H, DesNoyers, M.L., Lee, M.L., Goldstein, C., Friedman, T.C. (2018) Metabolic Parameters in Smokers Undergoing Smoking Cessation. Clin. Endocrinology.
Mojtahedzadeh, M., Shaesteh, N., Haykani, M., Shahinian, H.K., Nachnani, R., Saidian, J., Thomas, A., Lee, M.L., McCutcheon, I.E., Friedman, T.C. (2018) Low-dose and Standard Overnight and Low Dose-Two Day Dexamethasone Suppression Tests in Patients with Mild and/or Episodic Hypercortisolism. Clin. Endocrinology.

RESEARCH PAPERS-PEER-REVIEWED (In preparation):

Eugenio, F., Mangubat, M. Zopey, M., Shaheen, M., Friedman, T.C. (2018) The use of protocol-based dosing of methimazole in a safety-net endocrinology clinic in patients with Grave’s disease. J. Clin. Endo Metabolism

RESEARCH PAPERS (NON-PEER-REVIEWED)

None

ABSTRACTS

Gal, J., Basile, A. and Friedman, T.C. (1979) In Vitro Reductive Metabolism of N-nitrosodibenzylamine. Pharmacologist 21: 191.
Gal, J., Harper, T., Friedman, T.C. and Thompson, J.A. (1980) Stereoselective Reduction of Chiral Ketones to Chiral Alcohols by Rabbit Liver Cytosol. Pharmacologist 22: 242.
Friedman, T. C., Orlowski, M. and Wilk, S. (1983) Inhibition of Prolyl Endopeptidase by Benzyloxycarbonyl-prolyl-prolinal In Vivo. Fed. Proc. 42: 357.
Friedman, T.C., Davies, T. F. and Wilk, S. (1985) Inhibitor Stimulated Increase in Pyroglutamyl Peptide Hydrolase in GH3 Cells. Fifth Int. Washington Spring Symposium. Neural and Endocrine Peptides and Receptors. Abst. #189.
Wilk, S. and Friedman, T. C. (1985) Active-site Directed Inhibitors of TRH-Degrading Enzymes. Fifth Int. Washington Spring Symposium. Neural and Endocrine Peptides and Receptors. Abst. #142.
Wilk, S., Friedman, T. C. and Wilk, E. (1986) Purification and Properties of Rabbit Brain “Thyroliberinase”, a Membrane-Bound Thyrotropin-Releasing Hormone Degrading Enzyme. Fed. Proc. 45: 796.
Mixson, A., Friedman, T., Doppman, J., Oldfield, E. and Weintraub, B. (1990) Thyrotropin-Secreting Pituitary Carcinoma. Clinical Research 38:383A.
Friedman, T. C. (1990) Concentrations of Delta Sleep-Inducing Peptide in Inferior Petrosal Sinus and Simultaneous Peripheral Venous Samples in Patients with Cushing’s Syndrome. Endocrine Soc. 72:38.
Friedman, T.C., Thomas, P. and Fleisher, T. (1991) High Prevalence of Asplenism and Gallstones in Patients with Autoimmune Polyglandular Disease Type I. Endocrine Soc. 73:98.
Friedman, T.C., Kalogeras, K.T., Loh, Y.P., Doppman, J.L., Yanovski, J.A., Hardwick, D., Gold, P.W. and Chrousos, G.P. (1991) Concentrations of Arginine Vasopressin and Corticotropin-Releasing Hormone in Simultaneous Bilateral Inferior Petrosal Sinus and Peripheral Venous Samples in Patients with Cushing’s Disease. First Summer Neuropeptide Conference.
Friedman, T.C., Thomas, P., Fleisher, T., Feuillan, P., Parker, R. I., Cassorla, F. and Chrousos, G.P. (1991) Occurence of Asplenism and Gallstones in Patients with Autoimmune Polyglandular Disease Type I. NIH Research Festival.
Friedman, T.C., Kalogeras, K.T., Loh, Y.P., Doppman, J.L., Yanovski, J.A., Hardwick, D., Gold, P.W. and Chrousos, G.P. (1991) Concentrations of Arginine Vasopressin and Corticotropin-Releasing Hormone in Simultaneous Bilateral Inferior Petrosal Sinus and Peripheral Venous Samples in Patients with Cushing’s Disease. NIH Research Festival.
Friedman, T.C., Estivariz, F.E. and Loh, Y.P. (1991) Processing of Adrenocorticotropin by Two Proteases in Bovine Intermediate Lobe Secretory Vesicle Membranes: An Acidic, Tetrabasic-Residue Specific, Calcium-Stimulated Serine Protease and a Kex2/PC2-like Protease. 31th Annual Meeting of the American Society for Cell Biology. Abst. #1749.
Friedman, T.C., Hardwick, D., Garcia-Borreguero, D. and Loh, Y.P. (1992) Abnormal Thermoregulation in Patients with Cushing’s Syndrome. Endocrine Soc. 74:855.
Loh, Y.P., Friedman, T.C. and Estivariz, F.E. (1992) Identification and Partial Purification of Two Adrenocorticotropin-Processing Enzymes in Bovine Intermediate Lobe Secretory Vesicle Membranes. Endocrine Soc. 74:933.
Loh, Y.P., Friedman, T.C., and Estivariz, F.E.. (1992) Characterization of Endoprotease and Carboxypeptidase ACTH-Processing Activities in Bovine Intermediate Lobe Secretory Vesicle Membranes. Second Summer Neuropeptide Conference.
Friedman, T.C., Estivariz, F.E. and Loh, Y.P. (1992) Characterization of Endoprotease and Carboxypeptidase ACTH-Processing Activities in Bovine Intermediate Lobe Secretory Vesicle Membranes. Ninth International Congress of Endocrinology.

^18. Friedman, T.C., Hardwick, D., Garcia-Borreguero, D. and Loh, Y.P. (1992) Abnormal Thermoregulation in Patients with Cushing’s Syndrome. International Symposium on Endocrinology Under 35. Abst. #11.

Friedman, T.C., Estivariz, F.E. and Loh, Y.P. (1992) Characterization of Endoprotease and Carboxypeptidase ACTH-Processing Activities in Bovine Intermediate Lobe Secretory Vesicle Membranes. NIH Research Festival.
Mastorakos, G., Kokia, E., Webster, E.L., Friedman, T.C., Adashi, E.Y., and Chrousos, G.P. (1992) Ovarian Corticotropin-Releasing Hormone and its Potential Role. NIH Research Festival.
Friedman, T.C., Chen, H.C., and Loh, Y.P. (1992) A Unique Serine Carboxyl-Terminal Adrenocorticotropin-Cleaving Enzyme in Bovine Intermediate Lobe Secretory Vesicle Membranes. 32nd Annual Meeting of the American Society for Cell Biology. Abst.#1122
Friedman, T.C., Garcia-Borreguero, D., Hardwick, D., Akuete, C., Stambuk, M., Green, E., and Starkman, M.N. (1993) Circadian Rhythm of Plasma Delta Sleep-Inducing Peptide in Humans: Evidence for Correlation with Body Temperature But Not Sleep Stage. Endocrine Soc. 75:855.
Nillni, E.A., Friedman, T.C., Todd, R.B., Birch, N.P., and Loh, Y.P. (1993) Enzymatic Conversion of ProTRH by Secretory Vesicle Membranes and Partially Purified PC1 Enzyme. Endocrine Soc. 75:1696.
Azaryan, A.V., Wong, M., Friedman, T.C., Cawley, N.X., Estivariz, F.E., Chen, H.-C. and Loh, Y.P. (1993) Characteristics of YAP3, a New Prohormone Processing Aspartic Protease from S. Cerevisae. 5th Aspartic Protease Conference.
Friedman, T.C., Kalogeras, K.T., Loh, Y.P and Birch, N.P.. (1993) In Vitro Processing of POMC by Purified Recombinant PC1. 23rd Annual Meeting Society for Neuroscience. Abstract #441.6.
Friedman, T.C., Loh, Y.P and Birch, N.P. (1993) In Vitro Processing of POMC by Purified Recombinant PC1. NIH Research Festival.
Newman, T., Friedman, T.C., Mastorakos, G., Bouzas, E.A., Mullen, N.M., Horton, E. and Chrousos, G.P. (1994) Carbohydrate Metabolism, Bone Density and Ophthalmologic Findings in Endogenous Hypercortisolism. American Society for Clinical Investigation Abstract #A-EN-0053.
Friedman, T.C. and Yanovski, J.A. (1994) Plasma Free Cortisol in Patients with Cushing Syndrome, Pseudo-Cushing States and Normal Volunteers. Endocrine Soc. 76:355.
Yanovski, J., Yanovski, S,. Friedman, T., Harrington, L. and Chrousos, G. (1994) Differences in the Hypothalmic-Pituitary-Adrenal (HPA) Axis of Blacks and Whites. Endocrine Soc. 76:39.
Mastorakos, G., Scopa, C.D., Vryonidou, A., Friedman, T.C., Phenekos, C., and Chrousos, G.P. (1994) Presence of Immunoreactive Corticotropin Releasing Hormone (CRH) in Normal and Polycystic Human Ovaries. Endocrine Soc. 76:1667.
Friedman, T.C., Gordon, V.M., Leppla, S.H., Klimpel, K.R., Birch, N.P. and Loh, Y.P. (1994) In Vitro Processing of Anthrax Toxin Protective Antigen by Recombinant PC1(SPC3) and Bovine Intermediate Lobe Secretory Vesicle Membranes. The Gordon Research Conference on Hormonal and Neural Peptide Biosynthesis.
Friedman, T.C., Yanovski, J.A., Morris, J., Alvarez, J.F., and Kalogeras, K.T. (1994) Arginine Vasopressin Concentrations in the Inferior Petrosal Sinuses of Normal Volunteers and Patients with Cushing Disease. First World Congress on Stress, Abstract #69.
Garcia-Borreguero, D., Friedman, T., Neuhaus, I., Munson, P., Chrousos, G.P., and Kling, M. (1994) Pattern of Secretion of ACTH Pulses During REM Sleep in Healthy Adults. Preliminary Results. First World Congress on Stress, Abstract #74.
Taymans, S.E., DeVries, A.C., Friedman, T.C., Jayasvasti, V., Carter, C.S., and Chrousos, G.P. (1994) HPA Axis Hormones in Monogamous Vs. Polygamous Voles. First World Congress on Stress, Abstract #256.
Yao, P.D., Yanovski, J.A., Friedman, T.C., de la Paz, M., Bargas, L.R., Foroughi, A., Doppman, J.L., Kalogeras, K.T.(1994) The Role of Posterior Pituitary Hormones in the Regulation of the Hypothalamic-Pituitary-Adrenal Axis in the Inferior Petrosal Sinuses of Normal Human Subjects. First World Congress on Stress, Abstract #284.
Friedman, T.C., Cool, D.R., Jayasvasti, V., Louie, D., and Loh. Y.P. (1995) Processing of POMC in GH3 Cells: Insights from Antisense Experiments. Cedars-Sinai Research Institute-3rd Annual Retreat, Abstract #14.

*37. Friedman, T.C., Cool, D.R., Jayavasti, V., Louie, D., and Loh. Y.P. (1995) Processing of POMC in GH3 Cells: Insights from Antisense Experiments. Endocrine Soc. 77:OR13-2.

Mastorakos, G., Bouzas, E.A., Silver, P.B., Sartani, G., Friedman, T.C., Chan, C-C., Caspi, R.C., and Chrousos, G.P. (1995) Immune Corticotropin Releasing Hormone (CRH) is Present in the Eyes of and Promotes Experimental Autoimmune Uveoretinitis (EAU) in Rodents. Endocrine Soc. 77:OR15-2.
Mastorakos, G., Skopa, C.D., Kao, L.C., Vryonidou, A., Friedman, T.C., Kattis, D., Phenekos, C., Rabin, D., and Chrousos, G.P. (1995) Presence of Immunoreactive Corticotropin Releasing Hormone (CRH) in Human Endometrium. Endocrine Soc. 77:P1-105.
Dorn, L.D., Friedman, T.C., Gold, P.W., and Chrousos, G.P. (1995) The Post Cure Longitudinal Course of Psychopathology in Cushing Syndrome. Endocrine Soc. 77:P2-167.
Yanovski, J.A., Friedman, T.C., Nieman, L.K., Doppman, J.L., Cutler, Jr., G.B., Chrousos, G.P., and Kalogeras, K.T. (1996) Arginine Vasopressin in the Inferior Petrosal Sinuses of Patients with Cushing Disease, Ectopic ACTH Syndrome and Adrenal Adenomas. Tenth International Congress of Endocrinology P3-591.
Nie, Y. and Friedman, T.C. (1998) Regulation of PC1 and PC2 by Morphine and Naltrexone: Implication in the Homeostatic Response to Opiate Addiction. Endocrine Soc. 80:P1-75.

*43. Li, Q.-L., Jude, M., and Friedman, T.C. (1998) Regulation of the Prohormone Convertase 1 (PC1) by JAK/STAT related cytokines. Endocrine Soc. 80:OR51-6.

Friedman, T.C., Readhead, C.W., and Govan, III, H.L. (1998) Prohormone Convertase 4 (PC4) Isoforms in Testicular Cell Lines. Endocrine Soc. 80: P2-67.
Yanovski, J.A.,Miller, K.D., Friedman, T.C., Jones, E., Chrousos, G.P., and Falloon, J. (1998) HPA-Axis Function in HIV+ Patients with Indinavir-Induced Lipodystrophy. Endocrine Soc. 80:P2-543.
Shimon, I., Yan, X., Ren, S.G., Magoffin, D.A., Friedman, T.C., and Melmed, S. (1998) Long Leptin Receptor Isoform is Selectively Expresed in Human Fetal Pituitary and Pituitary Adenomas and Signals Fetal Pituitary Growth Hormone Secretion. Endocrine Soc. 80:P2-211.
Li, Q.-L., Jude, M., and Friedman, T.C. (1998) Regulation of PC1 by JAK/STAT-related cytokines. 5th International Pituitary Congress.
Garcia-Borreguero, D., Friedman, T.C., Chrousos, G.P., and Wehr, T.A. (1998) Withdrawal of glucocorticoids increases REM-sleep latency in patients with adrenal insufficiency. J. Sleep Res. 7: Supplement 2.
Nie, Y., Nakashima, M., Perfetti, R., Jansen, E., Plagova, M., Pipeleers, D., and Friedman, T.C. (1999) Regulation of Pancreatic PC1 in Diabetic Rats. Endocrine Soc. 81:P2-231.
Li, Q.-L., Brent, G., Wilber, J.F., Jansen, E., and Friedman, T.C. (1999) Interactions Between the Prohormone Convertase 2 (PC2) Promoter and the Thyroid Hormone Receptor. Endocrine Soc. 81:P2-662.
Friedman, T.C., Nakashima, M., Li, Q.-L., Nie, Y., Perfetti, R. and Friedman, T.C. (2000) Regulation of Pancreatic PC1 and PC2 Associated with Increased GLP-1 in Diabetic Rats. Endocrine Soc. 82:350.
Brubaker, P.L., Nakashima, M., Li, Q.-L., Nie, Y., Perfetti, R. and Friedman, T.C., (2000) Increased Pancreatic PC1 and PC2 are Associated with Increased GLP-1 in Diabetic Rats. Canadian Diabetes Assoc.

53 Ahmat, A.T., Brent, G.A., and Friedman, T.C., (2001) Treatment of Amiodarone-induced Hypothyroidism by Triiodothyronine. Endocrine Soc. 82:MTP350.

Friedman, T.C., Nie, Y., Nakashima, M., Li, Q.-L., Chen, F., and Brubaker, P. (2001) Regulation of Pancreatic PC1 and PC2 Associated with Increased GLP-1 in Diabetic Rats and Pancreatic Cell Lines. J. Invest. Med. 49:61S.

*55. Echeverry, D.M. and Friedman, T.C. (2001) Glucocorticoid-Remedial Aldosteronism: Nuances and Clues to the Diagnosis. Endocrine Soc. 83:M58-2.

Liu, Y.J., Nakagawa, Y. , Wang, Y., Toya, K. , Friedman, T.C., Li, R.S. and Ohzeki, T. (2001) Reduction of 11b-Hydroxysteroid Dehydrogenase Type 1 Messenger Ribonucleic Acid Expression in Livers of ob/ob Mice. Endocrine Soc. 83:P1-299.
Friedman, T.C., Li, Q.-L., Shen, X., Lindberg, I. (2001) Prohormone Convertase 2 (PC2) Enzymatic Activity and its Regulation in Endocrine Cells. Endocrine Soc. 83:P3-361.
Liu, Y.J., Lutfy, K., Steiner, D.F., Friedman, T.C., (2002) Nocioception, Tolerance and Dependence in PC2 Knockout Mice. Endocrine Soc. 84:P1-191.
Shen , X., Li, Q.-L., Jansen, E., Brent, GA., Friedman, T.C. (2002) Interactions Between the Prohormone Convertase 1 (PC1) Promoter and Thyroid Hormone. Endocrine Soc. 84:P2-518.
Wang, C., Kipnes, M., Matsumoto, A., Dobbs, A.S., Cunningham, G., Katznelson, L., Weber, T.J., Friedman, T.C., Snyder, P. (2002) Novel Testosterone Bioadhesive Buccal Tablet – Pharmacokinetics and Safety Evaluation. Endocrine Soc. 84:P2-645.

*^61. Lutfy, K., Liu, Y.J., Steiner, D.F., Furutu, M., Friedman, T.C., (2002) Nocioception, Tolerance and Dependence in PC2 Knockout Mice. 33^rd International Narcotics Research Conference. S13.

Friedman, T.C., Davoudi, S., Daigle, K., Barron, D.S., Lee, M.L., Poland, R.E. (2003) Renin-Aldosterone Axis and Orthostatic Hypotension in Patients with CFS. 6th International Conference on Chronic Fatigue Syndrome, Fibromyalgia and Related Illnesses. Physiology Abstracts.
Friedman, T.C., Zuckerbraun, E., Storer, T., Berman, J., Magliano, L., Woodhouse, L., Bhasin, S. (2003) Muscle strength, physical and sexual function in women with hypopituitarism. 8th International Pituitary Congress. P71.
Liu, Y., Nakagawa, Y., Wang, Y., Li, R., Ohzeki, T., Friedman, T.C. (2003) The Interaction of Leptin with 11b-Hydroxysteroid Dehydrogenase Type 1 in Hepatocytes May Mediate the Obesity Phenotype of Ob/Ob Mice. Endocrine Soc. 85: P1-444.
Friedman, T.C., Zuckerbraun, E., Ghanaat, F., Daigle, K., Barron, D.S., Poland, R.E. (2003) High Prevalence of Renin-Aldosterone Axis Abnormalities in Patients with Chronic Fatigue Syndrome (CFS). Endocrine Soc. 85:P1-533.
Sanchez, V.C., Goldstein, J., Stuart, R., Munzberg, H., Friedman, T.C., Liu, Y., Bjorbaek, C., Nillni, E.A. (2003) Regulation of the Hypothalamic Prohormone Convertases 1 and 2 Expression by Fasting and Leptin Endocrine Soc. 85:P3-113.
Choi, H.H., Friedman, T.C. (2003) Mysterious Suprasellar Mass Causing Hypopituitarism. Endocrine Soc. 85:P3-648.

*68. Tripathi, P.V., Shen, X., Friedman, T.C. (2004) Role Of Prohormone Convertase 1 In Diabetes: Studies Using Transgenic Mice. J. Invest. Med. 52 (Supp. 1):S15.

*69. Kim, H.S., Zuckerbraun, E., Daigle, K., Lee, M.L., Friedman, T.C. (2004) High Prevalence of Renin-Aldosterone Axis Abnormalities in Patients with Chronic Fatigue Syndrome (CFS). J. Invest. Med. 52 (Supp. 1):S23.

*70. Zuckerbraun, E., Kim, H.S., Storer, T., Berman, J., Magliano, L., Woodhouse, L., Bhasin, S., Friedman, T.C. (2004) Muscle strength, physical, sexual and psychological function in women with hypopituitarism. J. Invest. Med. 52 (Supp. 1):S56.

*71. Farasat, S., Tripathi, P.V., Lutfy, K., Friedman, T.C. (2004) Alteration in PC2 activity after short and long-term morphine exposure in GH3 cells. J. Invest. Med. 52 (Supp. 1):S24.

Tripathi, P.V., Shen, X., Liu, Y., Lutfy, K., Friedman, T.C. (2004) Alterations in weight and blood glucose in PC1 transgenic mice overexpressing PC1 behind the glucagon promoter. Endocrine Soc. 86:P1-20.
Liu, Y.J., Nakagawa, Y., Wang, Y., Friedman, T.C. (2004) Increased Glucocorticoid Receptor and 11b-hydroxysteroid Dehydrogenase Type 1 Expression in Hepatocytes May Contribute to the Phenotype of Type 2 Diabetes in Db/Db Mice. Endocrine Soc. 86:P1-65.
Roy, R., Friedman, T.C. (2004) Subclinical Adrenal Insufficiency-A Disease, Like Subclinical Hypothyroidism, Whose Time Has Come. Endocrine Soc. 86:P3-574.
Friedman, T.C. (2004) Overnight Dexamethasone Suppression Test for the Diagnosis of Cushing’s Syndrome: A Test Whose Time Has Passed. Endocrine Soc. 86:P3-401.
Friedman, T.C., Zuckerbraun, E., Daigle, K., Shahinian, H. (2004) The changing face of Cushing’s syndrome: mild and periodic cases makes the diagnosis more difficult. Endocrine Soc. 86:P3-408.
Patel, P.M., Shahinian, H. Friedman, T.C. (2004) Cushing’s Disease is not necessarily a progressive and fatal disease: A case of Cushing’s Disease Documented Untreated for 26 years. Endocrine Soc. 86:P3-565.

*78. Baquir, B., Friedman, T.C., Lutfy, K. (2004) Expression of CRE-responsive Genes in Brain Regions after Chronic Morphine Exposure. The first annual NIDDK undergraduate research conference. Poster Session 1 Abstract 3.

*^79. Garcia, M., Zuckerbraun, E., Tran, B., Berman, J., Bhasin, S., Friedman, T.C. (2005) Decreased Sexual Function And Testosterone Levels In Women With Hypopituitarism. J. Invest. Med. 53 (Supp. 1):119.

*80. Baquir, B., Tran, B., Tripathi, P., Farasat, S., Friedman, T.C., Lutfy, K. (2005) Expression Of CRE-Response Genes In Brain Regions After Chronic Morphine Exposure. (2005) J. Invest. Med. 53 (Supp. 1):222.

*81. Zuckerbraun, E., Garcia, M., Tran, B., Bhasin, S., Friedman, T.C. (2005) Comparison Of Cognitive Function And Quality Of Life In Women With Hypopituitarism: Role Of Androgens. J. Invest. Med. 53 (Supp. 1):399.

*82. Brown, M.C., Lutfy, K., Tran, B., Friedman, T.C., (2005) Repeated Stress May Alter The Ability Of Nicotine To Activate The Hypothalamic-Pituitary Adrenal Axis. J. Invest. Med. 53 (Supp. 1):404.

*^83. Garcia, M., Zuckerbraun, E., Berman, J., Bhasin, S., Friedman, T.C. (2005) Decreased Sexual Function And Testosterone Levels In Women With Hypopituitarism. Endocrine Soc. 87:OR21-3.

^84. Espinosa, V.P., Tripathi, P.V., Lutfy, K., Shen, X., Friedman, T.C., (2005) Role Of Prohormone Convertase 1 In Obesity And Diabetes: Studies Using Transgenic Mice Overexpressing PC1 Using A Proglucagon Promoter. Endocrine Soc. 87:P1-1.

Dhanvantari, S., McGirr, R., Mugimba, A., Ejbick, C.E., Carter, D.E., Andrews, J.D., Nie, Y., Friedman, T.C. (2005) Remodeling of the Regulated Secretory Pathway in TC1-6 Cells After Long-Term Exposure to High Glucose. Endocrine Soc. 87:P1-2.
Patel, S.S., Pall, M.E., Azziz, R., Friedman, T.C., (2005) Androgen levels in Women with Cushing’s Syndrome and the Polycystic Ovarian Syndrome. Endocrine Soc. 87:P2-363.
Patel, P.M., Shahinian, H., Friedman, T.C., (2005) Pituitary “Incidentalomas” are not Completely Incidental and May Cause Growth Hormone Deficiency. Endocrine Soc. 87:P2-534.
Nerio, N., Costa, L., Tran, B., Friedman, T.C., (2005) An Enhanced Paradigm for Oral Self-Selection of Nicotine. Endocrine Soc. 87:P3-174.

^89. Anghel, A., Lutfy, K., Liu, Y., Nie, Y., Friedman, T.C., (2005) Regulation of PC1/3 and PC2 by morphine: implication for the switch from drug use to drug abuse. 36^thInternational Narcotics Research Conference. T49.

^90. Aimiuwu, O, Friedman, T.C., (2005) The Use of the CRH-antagonist, Astressin, to Inhibit the Nicotine-stimulated Release of ACTH and Corticosterone. Frontiers in Addiction Research: 2005 NIDA Mini-convention. #41.

^91. Costa, L. Friedman, T.C., (2005) Genes and Proteins in Opiate Use. Frontiers in Addiction Research: 2005 NIDA Mini-convention. #41.

*^92. Garcia, M., Zuckerbraun, E., Berman, J., Friedman, T.C. (2006) Differences In Subjective And Objective Sexual Function Between Hispanic And Non-Hispanic Women. J. Invest. Med. 54 (Supp. 1):421.

*93. Sahasranam, P., Patel, P., Shahinian, H., Friedman, T.C. (2006) Pituitary “Incidentalomas” Are Not Completely Incidental And Cause Growth Hormone Deficiency. J. Invest. Med. 54 (Supp. 1):426.

Waugh, K., Bazargan, S., Friedman, T.C. (2006) The Correlation Between Drug and Alcohol Abuse and the Length of Psychiatric Inpatient Stay among Schizophrenic Patients. David Geffen School of Medicine at UCLA Third Annual Scholarship Day. Abstract #33

*95. Garcia, M, Zuckerbraun, E, Bhasin, S, Berman J, Friedman T.C. (2006) Decreased Subjective and Objective Measurements of Sexual Function and Testosterone Levels in Hypopituitary Women. Gynecological Endocrinology, 22 (Supp. 1). 2006.

Garcia, M., Zuckerbraun, E., Hsia, S.H., Friedman, T.C. (2006) Differences in the Lipid Profile and Testosterone Levels in Hypopituitary and Non-Hypopituitary Women. Endocrine Soc. 88:P2-632.
Garcia, M., Zuckerbraun, E., Bhasin, S., Friedman, T.C. (2006) Differences in Testosterone Levels, Subjective and Objective Sexual Function between Hispanic and Non-Hispanic Women. Endocrine Soc. 88:P3-542.
Friedman, T.C., Zuckerbraun, E., Lee, M.L., Shahinian, H.K. (2006) Dynamic Pituitary MRI Has High Positive and Negative Predictive Value for the Diagnosis of Mild Cushing’s Syndrome and Should Be Part of the Initial Workup. Endocrine Soc. 88:P2-730.
Ansari, A.N., Mahmood, G.A., Friedman, T.C (2006) Genetic Screening in MEN Syndrome Detects Predisposition to Pheochromocytoma and Hyperparathyroidism and Favorably Influences the Ultimate Course of the Disease: An Occult Case of MEN 2A Syndrome Endocrine Soc. 88:P2-903.
Liu, Y.J., Wang, Y., Nerio, N., Friedman, T.C. (2006) Reduction of Hepatic Glucocorticoid Receptor Expression by the Liver X Receptor Agonist T0901317 Ameliorates Diabetic Syndrome in db/db Mice. Endocrine Soc. 88:P1-308.

^101. Aimiuwu, O, Anghel, A., Nerio, N., Lutfy, K. Friedman, T.C., (2006) Stress’ Ability To Alter Chronic Nicotine’s Effect on the HPA Axis. Frontiers in Addiction Research: 2006 NIDA Mini-convention.

*^102. Gastelum, CG, Zuckerbraun, E., Lee, M, Kabil, M, Shahinian, H., Friedman, T.C. (2007) Dynamic Pituitary Magnetic Resonance Imaging Has High Positive and Negative Predictive Value For The Diagnosis Of Mild Cushing’s Syndrome and Should Be Part Of The Initial Workup. J. Invest. Med. 55 (Supp. 1):58.

*^103. Sahasranam, P., Tran, M., Friedman, T.C. (2007) Parathyroid Carcinoma: A Case Report. J. Invest. Med. 55 (Supp. 1):389.

*104. Sahasranam, P., Ballani, P., Friedman, T.C. (2007) Self-Regression Of Acromegaly: A Case Report. J. Invest. Med. 55 (Supp. 1):389.

Liu, Y., Wang, Y., Nerio, N., Anghel, A., Friedman, T.C. (2007) Carbenoxolone Inhibits Glucocorticoid Receptor Gene Expression in Response to Diet-Induced Insulin Resistance and Obesity in Mice. Endocrine Soc. 89:P4-329.
Gastelum, C. Friedman, T.C. (2007) High Prevalence of Episodic Hypercortisolism in 52 Consecutive Patients Cushing’s Syndrome. Endocrine Soc. 89:P4-46.
Liu, Y., Wang, Y., Nakagawa, Y., Chen, L., Ten, X. Friedman, T.C. (2007) Carbenoxolone Inhibition of Hepatic Glucocorticoid Availability in Response to the Development of Diet-Induced Obesity and Insulin Resistance in Mice. American Diabetes Association Scientific Sessions. 67:1809P.
Marquez, J., Zuckerbraun, E., Friedman, T.C. (2007). Physiologic Testosterone Replacement, the SCL-90R, and Women with Hypopituitarism. 3^nd annual Student Research Day, California State University Dominguez Hills, Carson, CA., p.53.
Liu, Y., Nakagawa, Y., Wang, Y., Liu, L., Ren, X., Lutfy, K., Friedman, T.C. (2008) Reduction of Hepatic Glucocorticoid Receptor and Hexose-6-Phosphate Dehydrogenase Expression Ameliorates Diet-Induced Obesity and Insulin Resistance in Mice. Endocrine Soc. 90:P1-155.
Anghel, A., Jamieson, C.A.M, Ren, X., Young, J., Ghods, D., Liu, Y., Lutfy, K., Friedman, T.C. (2008) Gene Expression Profiling Following Short-Term and Long-Term Morphine Exposure in Mice Uncovers Genes Involved in Food Intake. Endocrine Soc. 90: P1-171.
Thomson, S.G, Koren, G., Rieder, M.J., Friedman, T.C., Van Uum, S.H.M (2008) Hair Cortisol Measurement Provides a Historical Record of Hypercortisolism in Cushing’s Syndrome: Proof of Principle. Endocrine Soc. 90: P1-414.
Yuen, K.C.J., Cook, D.M., Sahasranam, P., Patel, P., Ghods, D.E., Shahinian, H.K., Friedman, T.C. (2008) Increased Prevalence of Growth Hormone and Other Pituitary Hormone Deficits in Adults with Non-Secreting Pituitary Microadenomas Despite Normal Serum IGF-I Levels. Endocrine Soc. 90: P3-782.
Friedman, T.C., Wang, W., Ghods, D., Lutfy, K., and Liu, Y. (2009) The Mechanisms of Nicotine-Induced Glucose Intolerance: Role in the High Prevalence of Cardiovascular Disease in Smokers. Endocrine Soc. 91: P2−476. (selected for a press release)

*113. Scott, J. Zuckerbraun, E., Lee, M.L., Morgan, M., Rapkin, A. Friedman, T.C. (2010) Testosterone Levels Subjective And Objective Sexual Function In Women With Hypopituitarism. J. Invest. Med. 58 (Num. 1):378.

Garcia, L., Seasholtz, S., Liu, Y., Lutfy, K, Mangubat, M., Friedman, T.C. (2010) The Effects of Nicotine on Visceral Fat Lipolysis Leading to Hepatic Steatosis and Insulin Resistance. Endocrine Soc. 92: P1−476.
Rapkin, A., Morgan, M., Scott, J. Zuckerbraun, E., Lee, M.L., Friedman, T.C. (2010) Serum Testosterone Levels Subjective And Objective Sexual Function In Women With Hypopituitarism. Endocrine Soc. 92: P2−418.
Liu, Y., Wang, Y., Nakagawa, Y., Wang, W., Virgous, C., Friedman, T.C. (2010) Elevated Hepatic Hexose-6-Phosphate Dehydrogenase and Glucose-6-Phosphate Transporter Expression May Contribute to the Development of Diabetic Syndrome in Diabetic Mice. Endocrine Soc. 92: P3−449.
Rajavashisth, T.B., Shaheen, M., Pan, D., Sinha, S.K., Ortega, J. Friedman, T.C., (2010) Decreased Prevalence of Diabetes in Marijuana Users: Data from NHANES III. American Diabetes Association. 70: 659P.

*118. Rajavashisth, T., Shaheen M, Pan D, Sinha S, Ortega J, Norris K, Friedman T. (2010) Decreased Prevalence of Diabetes in Marijuana Users: Data from NHANES III. The American Public Health Association (APHA) 138:217445.

*119. Niwenza, I., Vides, R., Mangubat, M., Garcia, L., Shen, R., Sinha-Hikim, AP, Friedman, T.C., Sinha-Hikim, I. (2011) Nicotine worsens high fat diet-induced hepatic and muscle steatosis in mice. J. Invest. Med. 59 (Num. 1):365.

Augustine, J., Schaffer, R., Friedman, T.C. (2011) Successful Treatment of Adrenal Remnant Tissue Using Alcohol Ablation in a Patient with Episodic Cushing Disease. Endocrine Soc. 93: P2−650.
Natividad, L., Escalante, E., Mangubat, M., Shin, C.S., Torres, O., Friedman, T.C. O’Dell, L.E. (2011) Age Differences in Food−Intake and the Weight−Suppressant Effects of Self−Administered Nicotine. Endocrine Soc. 93: P2−384.
Shayesteh, N., Mangubat, M., Haykani, M., Lee, M., McCutcheon, I., Friedman, T.C (2011) Low−Dose, Standard Overnight and Low−Dose Dexamethasone Suppression Test in Patients with Mild and/or Episodic Hypercortisolism. Endocrine Soc. 93: P3-531.

*123. Mangubat, M., Lyzlov, A., Nzenwa, I., Shen, R., Sinha Hikim, A., Friedman, T.C., Sinha-Hikim, I. (2011) Nicotine Induces Oxidative Stress and Exacerbates High Fat Diet (HFD)-Induced Hepatic Steatosis in a Mouse Model of Diet-Induced Obesity. Endocrine Soc. 93: OR04−1.

Du, H., Wang, W., Nakagawa, Y., Friedman, T.C., Liu, Y. (2011) Berberine Regulates Glucocorticoid Receptor and 11-Hydroxysteroid Dehydrogenase Expression in Murine Adipose Tissue and 3T3-L1 Adipocytes. Endocrine Soc. 93: P3-531.
Mangubat, M., Lutfy, K., Pulido, L., Stout, D., Davis, R., Seasholtz, S., Sinha-Hikim, A., Sinha-Hikim, I., O’Dell, L., Lyzlov, A., Liu, Y., Friedman, T.C. (2011) Effect of Nicotine on Body Composition in Mice. American Diabetes Association. 71:1596-P.
Shin, C.S., Mangubat, M., Lyzlov, A., Sinha-Hikim, A.P., Sinha-Hikim, I., Friedman, T.C., (2011) Nicotine Plus a High-Fat Diet Leads to Intramyocellular Fat Deposition in a Mouse Model of Diet-Induced Obesity. American Diabetes Association. 71: 2633-PO.
Escalante, E., Natividad, L.A., Okoro, A. Friedman, T.C., O’Dell, L.E. (2011) The Rewarding Effects of Nicotine Are Enhanced in Diabetic Rats. American Diabetes Association. 71: 2183-PO.
Liu, Y., Nakagawa, Y., Wang, Y. Wang, W., Ortega, J., Friedman, T.C. (2011) Tissue-Specific Dysregulation of Hexose-6-Phosphate Dehydrogenase and Glucose-6-Phosphate Transporter Expression in a Mouse Model of Type 2 Diabetes. American Diabetes Association 71: 1852-P.
Wang, W., Ortega, J., Porche, R., Lutfy, K., Friedman, T.C. Liu, Y. (2011) Reduction of Adipose 11β-Hydroxysteroid Dehydrogenase Type 1 and Hexose-6-Phosphate Dehydrogenase Expression Ameliorates Obesity and Insulin Resistance in Type 2 Diabetic db/db Mice. American Diabetes Association. 71: 1845-P.

*130. Gonzalez, S, Duran, P., Friedman, T., Davidson, M.B. (2012) The Effect of Six Months of Vitamin D Supplementation in Minorities with Pre-Diabetes and Hypovitaminosis D. J. Invest. Med. 60 (Num. 1):49.

Davidson, M.B, Duran, P., Lee, M.L., Friedman, T.C. (2012) The Effect of High Dose Vitamin D Supplementation in People with Pre-Diabetes and Hypovitaminosis D. American Diabetes Association. 72: 960-P.
Kermah, D., Shaheen, M., Pan, D., Friedman, T.C. (2012) Second-hand Smoke is Associated with Both Obesity and DM: Data from National Health and Nutrition Examination Survey, 2001-2006. American Diabetes Association. 72: 1414-P.
Friedman, T.C., Sinha-Hikim, I., Parveen, M., Mangubat, M., Shin, C.S., Lyzlov, Ivey, R., French, S.W., Sinha Hikim, A. (2012) Additive effects of nicotine and high fat diet on hepatic steatosis in mice involve oxidative stress and hepatocellular apoptosis and are mediated by abdominal lipolysis. American Diabetes Association. 72: 1785-P.
Kermah, D., Shaheen, M., Pan, D., Friedman, T.C. (2012) Second-hand Smoke is Associated with Both Obesity and DM: Multivariate Data Analysis from the National Health and Nutrition Examination Survey (NHANES), 2001-2006 Shows that Second-hand Smoke is Associated with Both Obesity and Diabetes Mellitus. Endocrine Soc. 94: SUN-192 (selected for a press-release).
Sinha Hikim, A., Sinha-Hikim, I., Parveen, M., Mangubat, M., Shin, C.S., Lyzlov, Ivey, R., French, S.W., Friedman, T.C. (2012) Additive effects of nicotine and high fat diet on hepatic steatosis in mice are mediated by abdominal lipolysis and involve oxidative stress and hepatocellular apoptosis. Endocrine Soc. 94: SUN-149.
Davidson, M.B, Duran, P., Lee, M.L., Friedman, T.C. (2012) The Effect of High Dose Vitamin D Supplementation in People with Pre-Diabetes and Hypovitaminosis D. Endocrine Soc. 94: Minority Affairs Poster Presentation
Liu, Y., Wang, Y., Nakagawa, Y., Wang, W., Lyzlov, A., Lutfy, K., and Friedman, T.C. (2012) Reduction of Glucose-6-Phosphate Transporter Induces Suppression of 11β-hydroxysteroid Dehydrogenase Type 1 Expression and Improvement of Glucose Homeostasis in a Diabetic Mouse. Endocrine Soc. 94: SAT-196.
Sinha-Hikim, I., Duran, P., Shen , R., Lee, M.L., Friedman, T.C., Davidson, M.B. (2013) Effects of long term supplementation of vitamin D on inflammation, cytokines, thrombosis and IGF-1 levels in minority subjects with pre-diabetes and hypovitaminosis D. Endocrine Soc. 95: SUN-268.
Lee, D.L., Lutfy, K., Ferrini, M.G. Friedman, T.C. (2013) PC2 Null Mice Show Up-Regulation of the Mu Opioid Receptor in Key Brain Regions Related to Nociceptive Information and Addictive Behaviors. Endocrine Soc. 95: MON-152 (press release).
Du, H., Wang, Y., Lutfy, K., Lee, D.L., Friedman, T.C., Liu, Y. (2013) 11β-hydroxysteroid Dehydrogenase Type 1 Gene Knockout Prevents the Development of Metabolic Syndrome in C57BL/6J mice. Endocrine Soc. 95: MON-686.

*141. Ivey, R., Sinha-Hikim, I., Desai, M., Shin, C.-S., Friedman, T.C., Sinha-Hikim, A.P. (2013) Additive Effects of Nicotine and High-Fat Diet On Hepatic Steatosis and Hepatocellular Apoptosis in Mice: Involvement of Caspase 2 and Inducible Nitric Oxide Synthase-Mediated Intrinsic Pathway Signaling. Endocrine Soc. 95: FP05-6/SAT-723 (featured poster)

Friedman, T.C., Sinha-Hikim, I., Ivey, R., Parveen, Shin, C.S., French, S.W., Sinha Hikim, A. (2013) Nicotine in combination with a high fat diet leads to muscle steatosis that is completed blocked by the lipolysis inhibitor, acipimox. American Diabetes Association. 73: 1980-P.
O’Dell, L.E., Natividad, L.A., Pipkin, J.A., Juardo, J., Torres, I., Friedman, T., Tenayuca, J., Nazarian, A. (2013) Enhanced nicotine self-administration and suppressed dopamine systems in a rat model of diabetes. American Diabetes Association. 73: 2896-PO.

*144. Friedman, T.C., Ivey, R., Lee, D.L., Sinha-Hikim, I. and Sinha-Hikim, A.P. (2014) Nicotine Plus a High-Fat Diet Leads to Abdominal Lipolysis with Resulting Hepatic and Muscle

Steatosis and Is Mediated By the Alpha 7 Nicotinic Receptor. Endocrine Soc. 96: OR15-4

Liu, Y., Yan, C., Wang, Y., Du, H., Fan, W., Mangubat, M., Zhong, A., Friedman, T.C., (2014) Regulatory Effects of RU486 on Glucocorticoid Metabolism and Insulin Signaling in Adipose Tissue from Corticosterone-Exposed Mice. Endocrine Soc. 96: SUN-1046.
Falz, M., Chalfant, V., Rea, I. Lee, D.L., Sinha-Hikim, I., Friedman, T.C. and Sinha-Hikim, A.P. (2015) Nicotine Plus a High-Fat Diet Increases Oxidative Stress and Triggers Cardiomyocyte Apoptosis in Male Mice. Endocrine Soc. 97: FRI-614.
Tian, S., Liu, X., Wu, Y., Ume, A., Navarro, G., Lee, D.L., Mangubat, M., Friedman, T.C., and Liu, Y. (2015) Reduction of Glucose-6-Phosphate Transporter Expression in Adipose Tissue Ameliorates Glucose Homeostasis and Insulin Resistance in Diabetic Mice. Endocrine Soc. 97: THR-635.
Hsia, S., DesNoyers, M., Lee, M.L., Goldstein, C., Friedman, T.C. (2015) Metabolic Effects of Smokers Undergoing Smoking Cessation. Endocrine Soc. 97: THR-622 (press release).
Ume, A., Duran, P., Driscoll, E., De La Cruz Mayhua, J., Nativi, C., Eugenio, F., Eugenio, J., Friedman, T.C. (2015) Obesity Group Visits: A New Approach for a Big Problem of Inner City Obesity. Endocrine Soc. 97: THR-562.

*150. Lee, D.L., Ume, A., Sinha-Hikim, I., Lee, P.W.-N., Friedman, T.C. and Sinha-Hikim, A.P. (2015) Nicotine stimulates muscle de novo lipogenesis in mice but causes intramyocellular lipid accumulation and mitochondrial abnormalities only when combined with a high-fat diet. Endocrine Soc. 97: OR28-2.

Yan, C., Liu, X., Navarro, G., Ume, A., Sims, C., Lutfy, K., Friedman, T.C., and Liu, Y. (2015) Increased 11ß-HSD1 and H6PDH Expression in Adipose Tissue May Contribute to Glucocorticoid-Induced Adipogenesis and Abdominal Obesity in Mice. American Diabetes Association. 75: 2155-PO.
Eugenio, F., Mangubat, M. Zopey, M., Shaheen, M., Friedman, T.C. (2016) Retrospective analysis of thyroid function tests in patients with Grave’s disease treated with protocol-based dosing of methimazole in a safety-net endocrinology clinic. Endocrine Soc. 98: SUN 273.
Duran, P., Driscoll, E., Alexander, N., Falz, M., Zopey, M., Navarro, G., Friedman, T.C. (2016) Obesity Group Visits Lower HbA1c in an Inner City Obese Population. Endocrine Soc. 98: FRI 613.
Friedman, T.C. Sims, C., Hasan, K., Lee, D.L. and Sinha-Hikim, A.P. (2016) Effects of Nicotine Plus Coke, Sugar Coke, or Diet Coke on Body Weight, Food Intake and Hepatic Steatosis. Endocrine Soc. 98: SUN 576.
Liu, Y., Fan, W., Ume, A., Sims, C., Lipeng, B., Navarro, G., Lutfy, K., Sinha-Hikim, A.P., Friedman, T.C.(2016) 11ß-Hydroxysteroid Dehydrogenase Type 1 shRNA Ameliorates Glucocorticoid-Induced Mouse Visceral Adiposity. Endocrine Soc. 98: SAT 641.

*156. Sinha-Hikim, I., Friedman, T.C., Falz, M., Chalfan, V., Rea, I., Lee, D., Sims, C., and Sinha-Hikim, A.P. (2016) Nicotine Plus a High-Fat Diet Triggers Cardiomyocyte Apoptosis in Male Mice By Inhibiting AMP-Activated Protein Kinase Independent of Fibroblast Growth Factor 21 and Silent Information Regulator 1. Endocrine Soc. 98: PP03-4, FRI 655.

Hasan, M.K., Friedman, T.C., Espinoza-Derout, J. Sims, C., Lee, D., Sinha-Hikim, I., and Sinha-Hikim, A.P. (2017) Additive Effects of Nicotine and High-Fat Diet on Hepatic Steatosis and Hepatocellular Apoptosis: Role of Alpha-7-nicotininc Acetylcholine Receptors. Endocrine Soc. 99: MON 518.
Hasan, M.K., Sinha-Hikim, A.P., Friedman, T.C. (2017) An in vitro model of nicotine-induced adipose tissue lipolysis and hepatic steatosis. Endocrine Soc. 99: MON 514.
Wang, F., Sims, C., Lee, D.L., Wang, Y. Ume, A., Lutfy, K., Sinha-Hikim, A.P., Friedman, T.C., Liu, Y.J. (2017) Inhibition of Hexose-6-Phosphate Dehydrogenase Expression in Subcutaneous Adipose Tissue Ameliorates Glucocorticoid – Induced Local Lipogenesis and Insulin Resistance in Male Mice. Endocrine Soc. 99: SUN 608.
Kermah, D., Shaheen, M., Pan, D., Friedman, T.C. (2017) Association Between Smoking and Sagittal Abdominal Diameter. RCMI.
Saldivar; P.A., Duran; P., Lee; M.L., Driscoll, E., Friedman, T.C. (2017) Texting Program’s Effect In An Obesity Medical Group Visit. RCMI #01.04.010.

*Oral presentation

^Travel award

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